UniProt O43255
E3 ubiquitin-protein ligase SIAH2 (O43255)
E3 ubiquitin-protein ligase SIAH2 (UniProt O43255): 2 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O43255
- Protein
- E3 ubiquitin-protein ligase SIAH2
- Experimental structures
- 2
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 2 · 0 records with a druggable one
Structures
3 records of O43255 in the MolNFT archive: 2 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5H9M | Crystal structure of siah2 SBD domain | x-ray diffraction | A, B | ZN, CL, UNX | — |
| 5H9M | Crystal structure of SIAH2 sbd domain | x-ray diffraction | A, B | — | — |
| O43255 | AlphaFold monomer V2.0 prediction for E3 ubiquitin-protein ligase SIAH2 (O43255) | predicted | A | — | 2 (best 0.41) |
Ligands
Experiment against prediction
- 5H9M chain B against the predicted model O43255: TM-score 0.89, RMSD 2.24 Å
- 5H9M chain B against the predicted model O43255: TM-score 0.89, RMSD 2.24 Å
- 5H9M chain A against the predicted model O43255: TM-score 0.88, RMSD 2.16 Å
- 5H9M chain A against the predicted model O43255: TM-score 0.88, RMSD 2.16 Å
Elsewhere
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