UniProt O41353
RNA-directed RNA polymerase catalytic subunit (O41353)
RNA-directed RNA polymerase catalytic subunit (UniProt O41353), EC 2.7.7.48: 12 experimental structures on GenesisL1, 3 ligands bound, 200 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O41353
- Protein
- RNA-directed RNA polymerase catalytic subunit
- EC
- 2.7.7.48
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 200 · 12 records with a druggable one
Structures
12 records of O41353 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8P0B | Thogoto virus polymerase in Mode B conformation and bound to 32-mer loop promoter RNA | electron microscopy | B | — | 14 (best 0.77) |
| 8P0G | Thogoto virus polymerase in Mode A conformation and bound to 35-mer loop promoter RNA | electron microscopy | B | MG | 13 (best 0.82) |
| 8P0U | Thogoto virus polymerase in Mode B conformation with defined endonuclease domain and bound to… | electron microscopy | B | MG | 15 (best 0.77) |
| 8Z85 | Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 1 | electron microscopy | B | — | 15 (best 0.75) |
| 8Z8J | Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 2 | electron microscopy | B | — | 18 (best 0.79) |
| 8Z8N | Cryo-EM structure of Thogoto virus polymerase in transcription pre-initiation conformation 3 | electron microscopy | B | — | 20 (best 0.79) |
| 8Z8X | Cryo-EM structure of Thogoto virus polymerase in a transcription initiation conformation | electron microscopy | B | G2P | 18 (best 0.84) |
| 8Z97 | Cryo-EM structure of Thogoto virus polymerase in a transcription elongation conformation | electron microscopy | B | V9G | 18 (best 0.84) |
| 8Z98 | Cryo-EM structure of Thogoto virus polymerase in a transcription reception conformation | electron microscopy | B | V9G | 18 (best 0.76) |
| 8Z9H | Cryo-EM structure of Thogoto virus polymerase in a transcription elongation-reception conformation | electron microscopy | B, I | V9G | 17 (best 0.87) |
| 8Z9Q | Cryo-EM structure of Thogoto virus polymerase in a replication reception conformation | electron microscopy | B | — | 15 (best 0.77) |
| 8Z9R | Cryo-EM structure of Thogoto virus polymerase in a replication elongation-reception conformation | electron microscopy | B, I | — | 19 (best 0.87) |
Ligands
Elsewhere
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