UniProt O35430
Amyloid-beta A4 precursor protein-binding family A member 1 (O35430)
Amyloid-beta A4 precursor protein-binding family A member 1 (UniProt O35430): 4 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, druggability and experiment against prediction…
- UniProt
- O35430
- Protein
- Amyloid-beta A4 precursor protein-binding family A member 1
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 1 · 0 records with a druggable one
Structures
5 records of O35430 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4DBB | The PTB domain of Mint1 is autoinhibited by a helix in the C-terminal linker region | x-ray diffraction | A | — | — |
| 4DBB | The ptb domain of MINT1 is autoinhibited by a helix in the C-terminal linker region | x-ray diffraction | A | — | — |
| 6KMH | The crystal structure of CASK/Mint1 complex | x-ray diffraction | C, D | IOD | — |
| 7XSJ | The structure of the Mint1/Munc18-1/syntaxin-1 complex | x-ray diffraction | C | — | 1 (best 0.35) |
| O35430 | AlphaFold monomer V2.0 prediction for amyloid-beta A4 precursor protein-binding family a member 1… | predicted | A | — | — |
Ligands
- IOD · Iodide ion · in 1 record
Experiment against prediction
- 4DBB chain A against the predicted model O35430: TM-score 0.78, RMSD 3.21 Å
- 4DBB chain A against the predicted model O35430: TM-score 0.78, RMSD 3.21 Å
- 7XSJ chain C against the predicted model O35430: TM-score 0.66, RMSD 1.03 Å
- 6KMH chain C against the predicted model O35430: TM-score 0.58, RMSD 3.29 Å
- 6KMH chain D against the predicted model O35430: TM-score 0.55, RMSD 3.05 Å
Elsewhere
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