UniProt O28951
Piwi protein AF_1318 (O28951)
Piwi protein AF_1318 (UniProt O28951): 11 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O28951
- Protein
- Piwi protein AF_1318
- Experimental structures
- 11
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 15 · 2 records with a druggable one
Structures
12 records of O28951 in the MolNFT archive: 11 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1W9H | The Structure of a Piwi protein from Archaeoglobus fulgidus. | x-ray diffraction | A | — | — |
| 1W9H | The structure of a piwi protein from archaeoglobus fulgidus. | x-ray diffraction | A | — | — |
| 1YTU | Structural basis for 5'-end-specific recognition of the guide RNA strand by the A. fulgidus PIWI… | x-ray diffraction | A, B | — | — |
| 1YTU | Structural basis for 5'-end-specific recognition of the guide RNA strand by the a. fulgidus piwi… | x-ray diffraction | A, B | — | — |
| 2BGG | The structure of a Piwi protein from Archaeoglobus fulgidus complexed with a 16nt siRNA duplex. | x-ray diffraction | A, B | — | — |
| 2BGG | The structure of a piwi protein from archaeoglobus fulgidus complexed with a 16NT siRNA duplex. | x-ray diffraction | A, B | — | — |
| 2W42 | The structure of a piwi protein from archaeoglobus fulgidus complexed with a 16NT DNA duplex. | x-ray diffraction | A, B | — | — |
| 2W42 | The structure of a piwi protein from archaeoglobus fulgidus complexed with a 16NT DNA duplex. | x-ray diffraction | A, B | — | — |
| 6T5T | Crystal structure of archaeoglobus fulgidus argonaute protein with cognate DNA oligoduplex… | x-ray diffraction | A | MG, CL, K | — |
| 6TUO | Crystal structure of archaeoglobus fulgidus argonaute protein with cognate DNA oligoduplex… | x-ray diffraction | A | MG, CL | — |
| 8OK9 | Heterodimeric complex of Archaeoglobus fulgidus Argonaute protein Af1318 (AfAgo) with DNA and… | x-ray diffraction | A | MG | 8 (best 0.81) |
| O28951 | AlphaFold monomer V2.0 prediction for piwi protein AF_1318 (O28951) | predicted | A | — | 7 (best 0.57) |
Ligands
Experiment against prediction
- 1YTU chain A against the predicted model O28951: TM-score 0.97, RMSD 1.34 Å
- 1YTU chain A against the predicted model O28951: TM-score 0.97, RMSD 1.34 Å
- 2BGG chain B against the predicted model O28951: TM-score 0.97, RMSD 1.36 Å
- 2BGG chain B against the predicted model O28951: TM-score 0.97, RMSD 1.36 Å
- 2W42 chain B against the predicted model O28951: TM-score 0.97, RMSD 1.40 Å
- 2W42 chain B against the predicted model O28951: TM-score 0.97, RMSD 1.40 Å
- 6T5T chain A against the predicted model O28951: TM-score 0.97, RMSD 1.49 Å
- 2W42 chain A against the predicted model O28951: TM-score 0.97, RMSD 1.48 Å
- 2W42 chain A against the predicted model O28951: TM-score 0.97, RMSD 1.48 Å
- 6TUO chain A against the predicted model O28951: TM-score 0.97, RMSD 1.53 Å
Elsewhere
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