UniProt O16810
Origin recognition complex subunit 1 (O16810)
Origin recognition complex subunit 1 (UniProt O16810): 15 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 76 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O16810
- Protein
- Origin recognition complex subunit 1
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 76 · 8 records with a druggable one
Structures
16 records of O16810 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4XGC | Crystal structure of the eukaryotic origin recognition complex | x-ray diffraction | A | — | 10 (best 0.85) |
| 4XGC | Crystal structure of the eukaryotic origin recognition complex | x-ray diffraction | A | — | — |
| 7JGR | Structure of Drosophila ORC bound to DNA (84 bp) and Cdc6 | electron microscopy | A | ATP, MG | 12 (best 0.88) |
| 7JGR | Structure of drosophila orc bound to DNA (84 bp) and CDC6 | electron microscopy | A | ATP, MG | — |
| 7JGS | Structure of drosophila orc bound to POLY(DA/DT) DNA and CDC6 (conformation 2) | electron microscopy | A | ATP, MG | — |
| 7JK2 | Structure of Drosophila ORC bound to poly(dA/dT) DNA and Cdc6 (conformation 1) | electron microscopy | A | ATP, MG | 12 (best 0.88) |
| 7JK2 | Structure of drosophila orc bound to POLY(DA/DT) DNA and CDC6 (conformation 1) | electron microscopy | A | ATP, MG | — |
| 7JK3 | Structure of Drosophila ORC bound to GC-rich DNA and Cdc6 | electron microscopy | A | ATP, MG | 10 (best 0.88) |
| 7JK3 | Structure of drosophila orc bound to gc-rich DNA and CDC6 | electron microscopy | A | ATP, MG | — |
| 7JK4 | Structure of Drosophila ORC bound to AT-rich DNA and Cdc6 | electron microscopy | A | ATP, MG | 9 (best 0.86) |
| 7JK4 | Structure of drosophila orc bound to at-rich DNA and CDC6 | electron microscopy | A | ATP, MG | — |
| 7JK5 | Structure of Drosophila ORC bound to DNA | electron microscopy | A | ATP, MG | 6 (best 0.87) |
| 7JK5 | Structure of drosophila orc bound to DNA | electron microscopy | A | ATP, MG | — |
| 7JK6 | Structure of Drosophila ORC in the active conformation | electron microscopy | A | ATP, MG | 10 (best 0.86) |
| 7JK6 | Structure of drosophila orc in the active conformation | electron microscopy | A | ATP, MG | — |
| O16810 | AlphaFold monomer V2.0 prediction for origin recognition complex subunit 1 (O16810) | predicted | A | — | 7 (best 0.63) |
Ligands
Experiment against prediction
- 7JGR chain A against the predicted model O16810: TM-score 0.99, RMSD 0.76 Å
- 7JGR chain A against the predicted model O16810: TM-score 0.99, RMSD 0.76 Å
- 7JK4 chain A against the predicted model O16810: TM-score 0.99, RMSD 0.76 Å
- 7JK4 chain A against the predicted model O16810: TM-score 0.99, RMSD 0.76 Å
- 7JGS chain A against the predicted model O16810: TM-score 0.99, RMSD 0.77 Å
- 7JK2 chain A against the predicted model O16810: TM-score 0.99, RMSD 0.78 Å
- 7JK2 chain A against the predicted model O16810: TM-score 0.99, RMSD 0.78 Å
- 7JK3 chain A against the predicted model O16810: TM-score 0.98, RMSD 0.90 Å
- 7JK3 chain A against the predicted model O16810: TM-score 0.98, RMSD 0.90 Å
- 7JK5 chain A against the predicted model O16810: TM-score 0.98, RMSD 0.91 Å
Elsewhere
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