UniProt O15554
Intermediate conductance calcium-activated potassium channel protein 4 (O15554)
Intermediate conductance calcium-activated potassium channel protein 4 (UniProt O15554): 8 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 64 pockets. Binding sites, druggability and experiment…
- UniProt
- O15554
- Protein
- Intermediate conductance calcium-activated potassium channel protein 4
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 64 · 4 records with a druggable one
Structures
9 records of O15554 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6CNM | Cryo-EM structure of the human SK4/calmodulin channel complex | electron microscopy | A, B, C, D | K, POV | 20 (best 0.82) |
| 6CNM | Cryo-EM structure of the human SK4/CALMODULIN channel complex | electron microscopy | A, B, C, D | K, POV | — |
| 6CNN | Cryo-EM structure of the human SK4/calmodulin channel complex in the Ca2+ bound state I | electron microscopy | A, B, C, D | K, POV | 20 (best 0.83) |
| 6CNN | Cryo-EM structure of the human SK4/CALMODULIN channel complex in the CA2+ bound state I | electron microscopy | A, B, C, D | K, POV | — |
| 6CNO | Cryo-EM structure of the human SK4/calmodulin channel complex in the Ca2+ bound state II | electron microscopy | A, B, C, D | — | 20 (best 0.84) |
| 6CNO | Cryo-EM structure of the human SK4/CALMODULIN channel complex in the CA2+ bound state II | electron microscopy | A, B, C, D | — | — |
| 6D42 | Crystal structure of the KCa3.1 C-terminal four-helix bundle (with copper) | x-ray diffraction | A, B | CU | — |
| 6D42 | Crystal structure of the KCA3.1 C-terminal four-helix bundle (with copper) | x-ray diffraction | A, B | CU | — |
| O15554 | AlphaFold monomer V2.0 prediction for intermediate conductance calcium-activated potassium channel… | predicted | A | — | 4 (best 0.64) |
Ligands
Experiment against prediction
- 6CNM chain A against the predicted model O15554: TM-score 0.91, RMSD 2.35 Å
- 6CNM chain A against the predicted model O15554: TM-score 0.91, RMSD 2.35 Å
- 6D42 chain A against the predicted model O15554: TM-score 0.91, RMSD 1.17 Å
- 6D42 chain A against the predicted model O15554: TM-score 0.91, RMSD 1.17 Å
- 6CNN chain A against the predicted model O15554: TM-score 0.86, RMSD 2.80 Å
- 6CNN chain A against the predicted model O15554: TM-score 0.86, RMSD 2.80 Å
- 6CNO chain A against the predicted model O15554: TM-score 0.85, RMSD 3.06 Å
- 6CNO chain A against the predicted model O15554: TM-score 0.85, RMSD 3.06 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.