UniProt O15446
DNA-directed RNA polymerase I subunit RPA34 (O15446)
DNA-directed RNA polymerase I subunit RPA34 (UniProt O15446): 9 experimental structures and 1 predicted model on GenesisL1, 9 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O15446
- Protein
- DNA-directed RNA polymerase I subunit RPA34
- Experimental structures
- 9
- Predicted models
- 1
- Pockets
- 9 · 4 records with a druggable one
Structures
10 records of O15446 in the MolNFT archive: 9 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7OB9 | Cryo-EM structure of human RNA Polymerase I in elongation state | electron microscopy | N | — | 2 (best 0.76) |
| 7OB9 | Cryo-EM structure of human RNA polymerase I in elongation state | electron microscopy | N | — | — |
| 7OBA | Cryo-EM structure of human RNA Polymerase I in complex with RRN3 | electron microscopy | N | — | 2 (best 0.81) |
| 7OBA | Cryo-EM structure of human RNA polymerase I in complex with RRN3 | electron microscopy | N | — | — |
| 7OBB | Cryo-EM structure of human RNA Polymerase I Open Complex | electron microscopy | N | — | 2 (best 0.76) |
| 7OBB | Cryo-EM structure of human RNA polymerase I open complex | electron microscopy | N | — | — |
| 7VBA | Structure of the pre state human RNA Polymerase I Elongation Complex | electron microscopy | N | — | — |
| 8A43 | Human RNA polymerase I | electron microscopy | M | — | 3 (best 0.78) |
| 8A43 | Human RNA polymerase I | electron microscopy | M | — | — |
| O15446 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase I subunit RPA34 (O15446) | predicted | A | — | — |
Experiment against prediction
- 8A43 chain M against the predicted model O15446: TM-score 0.81, RMSD 2.73 Å
- 8A43 chain M against the predicted model O15446: TM-score 0.81, RMSD 2.73 Å
- 7VBA chain N against the predicted model O15446: TM-score 0.70, RMSD 2.95 Å
- 7OB9 chain N against the predicted model O15446: TM-score 0.66, RMSD 3.28 Å
- 7OB9 chain N against the predicted model O15446: TM-score 0.66, RMSD 3.28 Å
- 7OBA chain N against the predicted model O15446: TM-score 0.65, RMSD 3.29 Å
- 7OBA chain N against the predicted model O15446: TM-score 0.65, RMSD 3.29 Å
- 7OBB chain N against the predicted model O15446: TM-score 0.64, RMSD 3.31 Å
- 7OBB chain N against the predicted model O15446: TM-score 0.64, RMSD 3.31 Å
Elsewhere
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