UniProt O15342
V-type proton ATPase subunit e 1 (O15342)
V-type proton ATPase subunit e 1 (UniProt O15342): 11 experimental structures on GenesisL1, 5 ligands bound, 11 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O15342
- Protein
- V-type proton ATPase subunit e 1
- Experimental structures
- 11
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 11 · 6 records with a druggable one
Structures
11 records of O15342 in the MolNFT archive: 11 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6WLW | The Vo region of human V-ATPase in state 1 (focused refinement) | electron microscopy | S | NAG, MAN, CLR, PTY, WSS | 5 (best 0.80) |
| 6WLW | The vo region of human V-ATPase in state 1 (focused refinement) | electron microscopy | S | NAG, MAN, CLR, PTY, WSS | — |
| 6WM2 | Human V-ATPase in state 1 with SidK and ADP | electron microscopy | S | NAG, MAN, CLR, PTY, WSS | 2 (best 0.80) |
| 6WM2 | Human V-ATPase in state 1 with sidk and ADP | electron microscopy | S | NAG, MAN, PTY, WSS | — |
| 6WM3 | Human V-ATPase in state 2 with SidK and ADP | electron microscopy | S | NAG | 1 (best 0.82) |
| 6WM3 | Human V-ATPase in state 2 with sidk and ADP | electron microscopy | S | NAG | — |
| 6WM4 | Human V-ATPase in state 3 with SidK and ADP | electron microscopy | S | NAG | 1 (best 0.84) |
| 6WM4 | Human V-ATPase in state 3 with sidk and ADP | electron microscopy | S | NAG | — |
| 7U4T | Human V-ATPase in state 2 with SidK and mEAK-7 | electron microscopy | S | NAG | 1 (best 0.82) |
| 7UNF | CryoEM structure of a mEAK7 bound human V-ATPase complex | electron microscopy | m | NAG, MAN | 1 (best 0.82) |
| O15342 | AlphaFold monomer V2.0 prediction for V-type proton ATPase subunit E 1 (O15342) | — | — | — |
Ligands
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 10 records
- MAN · alpha-D-mannopyranose · in 5 records
- PTY · Phosphatidylethanolamine · in 4 records
- WSS · tri(methyl)-[2-[[(2~{R})-2-[(~{Z})-octadec-9-enoyl]oxy-3-[(~{E})-1-oxidanylideneoctadec-9-enoxy]propoxy]-oxidanyl-phosphoryl]oxyethyl]azanium · in 4 records
- CLR · Cholesterol · in 3 records
Elsewhere
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