UniProt O15085
Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera (O15085)
Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2 chimera (UniProt O15085): 18 experimental structures and 1 predicted model on GenesisL1, 1 pocket. Binding sites, druggability and experiment against…
- UniProt
- O15085
- Protein
- Rho guanine nucleotide exchange factor 11, C-X-C chemokine receptor type 2…
- Experimental structures
- 18
- Predicted models
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
19 records of O15085 in the MolNFT archive: 18 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 1HTJ | Structure of the rgs-like domain from PDZ-rhogef | x-ray diffraction | F | — | — |
| 1HTJ | Structure of the rgs-like domain from PDZ-rhogef | x-ray diffraction | F | — | — |
| 1XCG | Crystal Structure of Human RhoA in complex with DH/PH fragment of PDZRHOGEF | x-ray diffraction | A, E | — | — |
| 1XCG | Crystal structure of human rhoa in complex with DH/PH fragment of pdzrhogef | x-ray diffraction | A, E | — | — |
| 2DLS | Solution structure of the PDZ domain of human Rho guanine nucleotide exchange factor 11 | solution nmr | A | — | — |
| 2DLS | Solution structure of the PDZ domain of human rho guanine nucleotide exchange factor 11 | solution nmr | A | — | — |
| 3KZ1 | Crystal Structure of the Complex of PDZ-RhoGEF DH/PH domains with GTP-gamma-S Activated RhoA | x-ray diffraction | A, B | — | — |
| 3KZ1 | Crystal structure of the complex of PDZ-rhogef DH/PH domains with GTP- gamma-S activated rhoa | x-ray diffraction | A, B | — | — |
| 3T06 | Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex… | x-ray diffraction | A, E | — | — |
| 3T06 | Crystal structure of the DH/PH fragment of pdzrhogef with N-terminal regulatory elements in complex… | x-ray diffraction | A, E | — | — |
| 5E6P | PlexinB2 cytoplasmic region/PDZ-RhoGEF PDZ domain complex | x-ray diffraction | B | — | — |
| 5E6P | PLEXINB2 cytoplasmic REGION/PDZ-rhogef PDZ domain complex | x-ray diffraction | B | — | — |
| 5JHG | Crystal structure of the complex between the human RhoA and the DH/PH domain of human ARHGEF11 | x-ray diffraction | A, E | — | — |
| 5JHG | Crystal structure of the complex between the human rhoa and the DH/PH domain of human ARHGEF11 | x-ray diffraction | A, E | — | — |
| 5JHH | Crystal structure of the ternary complex between the human RhoA, its inhibitor and the DH/PH domain… | x-ray diffraction | A, E | — | — |
| 5JHH | Crystal structure of the ternary complex between the human rhoa, its inhibitor and the DH/PH domain… | x-ray diffraction | A, E | — | — |
| 5TYT | Crystal Structure of the PDZ domain of RhoGEF bound to CXCR2 C-terminal peptide | x-ray diffraction | A, B, C, D | — | 1 (best 0.76) |
| 5TYT | Crystal structure of the PDZ domain of rhogef bound to CXCR2 C- terminal peptide | x-ray diffraction | A, B, C, D | — | — |
| O15085 | AlphaFold monomer V2.0 prediction for rho guanine nucleotide exchange factor 11 (O15085) | predicted | A | — | — |
Experiment against prediction
- 3KZ1 chain B against the predicted model O15085: TM-score 0.98, RMSD 0.97 Å
- 3KZ1 chain B against the predicted model O15085: TM-score 0.98, RMSD 0.97 Å
- 1HTJ chain F against the predicted model O15085: TM-score 0.97, RMSD 0.95 Å
- 1HTJ chain F against the predicted model O15085: TM-score 0.97, RMSD 0.95 Å
- 3KZ1 chain A against the predicted model O15085: TM-score 0.95, RMSD 1.58 Å
- 3KZ1 chain A against the predicted model O15085: TM-score 0.95, RMSD 1.58 Å
- 3T06 chain A against the predicted model O15085: TM-score 0.95, RMSD 1.63 Å
- 3T06 chain A against the predicted model O15085: TM-score 0.95, RMSD 1.63 Å
- 1XCG chain A against the predicted model O15085: TM-score 0.95, RMSD 1.70 Å
- 1XCG chain A against the predicted model O15085: TM-score 0.95, RMSD 1.70 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.