UniProt O15033
Apoptosis-resistant E3 ubiquitin protein ligase 1 (O15033)
Apoptosis-resistant E3 ubiquitin protein ligase 1 (UniProt O15033), EC 2.3.2.26: 4 experimental structures and 1 predicted model on GenesisL1, 36 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- O15033
- Protein
- Apoptosis-resistant E3 ubiquitin protein ligase 1
- EC
- 2.3.2.26
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 36 · 2 records with a druggable one
Structures
5 records of O15033 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6JX5 | Hect domain of AREL1 | x-ray diffraction | C, A, B | — | 19 (best 0.55) |
| 6JX5 | Hect domain of AREL1 | x-ray diffraction | C, A, B | — | — |
| 6LOH | Crystal structure of the catalytic domain of human ubiquitin ligase AREL1 | x-ray diffraction | A, B, C | — | 17 (best 0.81) |
| 6LOH | Crystal structure of the catalytic domain of human ubiquitin ligase AREL1 | x-ray diffraction | A, B, C | — | — |
| O15033 | AlphaFold monomer V2.0 prediction for apoptosis-resistant E3 ubiquitin protein ligase 1 (O15033) | predicted | A | — | — |
Experiment against prediction
- 6JX5 chain C against the predicted model O15033: TM-score 0.98, RMSD 1.00 Å
- 6JX5 chain C against the predicted model O15033: TM-score 0.98, RMSD 1.00 Å
- 6LOH chain B against the predicted model O15033: TM-score 0.98, RMSD 1.11 Å
- 6LOH chain B against the predicted model O15033: TM-score 0.98, RMSD 1.11 Å
- 6JX5 chain A against the predicted model O15033: TM-score 0.98, RMSD 1.14 Å
- 6JX5 chain A against the predicted model O15033: TM-score 0.98, RMSD 1.14 Å
- 6JX5 chain B against the predicted model O15033: TM-score 0.98, RMSD 1.16 Å
- 6JX5 chain B against the predicted model O15033: TM-score 0.98, RMSD 1.16 Å
- 6LOH chain C against the predicted model O15033: TM-score 0.97, RMSD 1.31 Å
- 6LOH chain C against the predicted model O15033: TM-score 0.97, RMSD 1.31 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.