UniProt O14958
Calsequestrin-2 (O14958)
Calsequestrin-2 (UniProt O14958): 8 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 42 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O14958
- Protein
- Calsequestrin-2
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 42 · 3 records with a druggable one
Structures
9 records of O14958 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2VAF | Crystal structure of Human Cardiac Calsequestrin | x-ray diffraction | A | — | — |
| 2VAF | Crystal structure of human cardiac calsequestrin | x-ray diffraction | A | — | — |
| 6OWV | Crystal structure of a Human Cardiac Calsequestrin Filament | x-ray diffraction | A | SO4, CL | 2 (best 0.63) |
| 6OWV | Crystal structure of a human cardiac calsequestrin filament | x-ray diffraction | A | SO4, CL | — |
| 6OWW | Crystal structure of a Human Cardiac Calsequestrin Filament Complexed with Ytterbium | x-ray diffraction | A, B, C, D, E, F, G, H | YB, SO4 | 20 (best 0.88) |
| 6OWW | Crystal structure of a human cardiac calsequestrin filament complexed with ytterbium | x-ray diffraction | A, B, C, D, E, F, G, H | YB, SO4 | — |
| 7F05 | Crystal structure of human cardiac calsequestrin bound with calcium | x-ray diffraction | A, C, B, D | CA | 20 (best 0.84) |
| 7F05 | Crystal structure of human cardiac calsequestrin bound with calcium | x-ray diffraction | A, C, B, D | CA | — |
| O14958 | AlphaFold monomer V2.0 prediction for calsequestrin-2 (O14958) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7F05 chain D against the predicted model O14958: TM-score 0.97, RMSD 1.30 Å
- 7F05 chain D against the predicted model O14958: TM-score 0.97, RMSD 1.30 Å
- 7F05 chain B against the predicted model O14958: TM-score 0.97, RMSD 1.30 Å
- 7F05 chain B against the predicted model O14958: TM-score 0.97, RMSD 1.30 Å
- 7F05 chain C against the predicted model O14958: TM-score 0.96, RMSD 1.42 Å
- 7F05 chain C against the predicted model O14958: TM-score 0.96, RMSD 1.42 Å
- 7F05 chain A against the predicted model O14958: TM-score 0.96, RMSD 1.44 Å
- 7F05 chain A against the predicted model O14958: TM-score 0.96, RMSD 1.44 Å
- 6OWV chain A against the predicted model O14958: TM-score 0.95, RMSD 1.48 Å
- 6OWV chain A against the predicted model O14958: TM-score 0.95, RMSD 1.48 Å
Elsewhere
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