UniProt O14187
Pre-mRNA-splicing factor spp42 (O14187)
Pre-mRNA-splicing factor spp42 (UniProt O14187): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 45 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O14187
- Protein
- Pre-mRNA-splicing factor spp42
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 2
- Pockets
- 45 · 3 records with a druggable one
Structures
5 records of O14187 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3JB9 | Cryo-EM structure of the yeast spliceosome at 3.6 angstrom resolution | electron microscopy | A | — | — |
| 3JB9 | Cryo-EM structure of the yeast spliceosome at 3.6 ångström resolution | electron microscopy | A | — | — |
| 9ESH | Structure of a B-state intermediate committed to discard (Bd-I state) | electron microscopy | A | IHP, GTP | 12 (best 0.89) |
| 9ESI | Structure of a B-state intermediate committed to discard (Bd-II state) | electron microscopy | A | IHP, GTP | 13 (best 0.88) |
| O14187 | AlphaFold monomer V2.0 prediction for pre-mRNA-splicing factor SPP42 (O14187) | predicted | A | — | 20 (best 0.81) |
Ligands
Experiment against prediction
- 9ESH chain A against the predicted model O14187: TM-score 0.98, RMSD 1.81 Å
- 3JB9 chain A against the predicted model O14187: TM-score 0.87, RMSD 3.45 Å
- 3JB9 chain A against the predicted model O14187: TM-score 0.87, RMSD 3.45 Å
- 9ESI chain A against the predicted model O14187: TM-score 0.87, RMSD 2.12 Å
Elsewhere
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