UniProt O08838
Amphiphysin (O08838)
Amphiphysin (UniProt O08838): 4 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O08838
- Protein
- Amphiphysin
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
5 records of O08838 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2VJ0 | Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, in complex… | x-ray diffraction | Q | — | — |
| 2VJ0 | Crystal structure of the alpha-adaptin appendage domain, from the AP2 adaptor complex, in complex… | x-ray diffraction | Q | — | — |
| 5M5T | Clathrin heavy chain N-terminal domain bound to a non-natural clathrin-box motif peptide (Amph4T1) | x-ray diffraction | E, F, G, H, I, J | — | 2 (best 0.41) |
| 5M5T | Clathrin heavy chain N-terminal domain bound to a non-natural clathrin-box motif peptide (AMPH4T1) | x-ray diffraction | E, F, G, H, I, J | — | — |
| O08838 | AlphaFold monomer V2.0 prediction for amphiphysin (O08838) | predicted | A | — | — |
Experiment against prediction
- 5M5T chain J against the predicted model O08838: TM-score 0.57, RMSD 1.11 Å
- 5M5T chain J against the predicted model O08838: TM-score 0.57, RMSD 1.11 Å
- 5M5T chain E against the predicted model O08838: TM-score 0.54, RMSD 0.85 Å
- 5M5T chain E against the predicted model O08838: TM-score 0.54, RMSD 0.85 Å
- 5M5T chain F against the predicted model O08838: TM-score 0.53, RMSD 0.81 Å
- 5M5T chain F against the predicted model O08838: TM-score 0.53, RMSD 0.81 Å
- 5M5T chain H against the predicted model O08838: TM-score 0.51, RMSD 0.84 Å
- 5M5T chain H against the predicted model O08838: TM-score 0.51, RMSD 0.84 Å
- 2VJ0 chain Q against the predicted model O08838: TM-score 0.51, RMSD 1.08 Å
- 2VJ0 chain Q against the predicted model O08838: TM-score 0.51, RMSD 1.08 Å
Elsewhere
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