UniProt O08795
Glucosidase 2 subunit beta (O08795)
Glucosidase 2 subunit beta (UniProt O08795): 37 experimental structures and 1 predicted model on GenesisL1, 3 ligands bound, 57 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O08795
- Protein
- Glucosidase 2 subunit beta
- Experimental structures
- 37
- Predicted models
- 1
- Ligands
- 3
- Pockets
- 57 · 16 records with a druggable one
Structures
38 records of O08795 in the MolNFT archive: 37 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5F0E | Murine endoplasmic reticulum alpha-glucosidase II | x-ray diffraction | B | CA | 2 (best 0.59) |
| 5F0E | Murine endoplasmic reticulum alpha-glucosidase II | x-ray diffraction | B | — | — |
| 5H9O | Complex of Murine endoplasmic reticulum alpha-glucosidase II with D-Glucose | x-ray diffraction | B, D | CA | 4 (best 0.60) |
| 5H9O | Complex of murine endoplasmic reticulum alpha-glucosidase II with D- glucose | x-ray diffraction | B, D | — | — |
| 5HJO | Murine endoplasmic reticulum alpha-glucosidase II with bound substrate analogue | x-ray diffraction | B, D | DGO, CA | 4 (best 0.61) |
| 5HJO | Murine endoplasmic reticulum alpha-glucosidase II with bound substrate analogue | x-ray diffraction | B, D | — | — |
| 5HJR | Murine endoplasmic reticulum alpha-glucosidase II with bound covalent intermediate | x-ray diffraction | B, D | CA | 4 (best 0.60) |
| 5HJR | Murine endoplasmic reticulum alpha-glucosidase II with bound covalent intermediate | x-ray diffraction | B, D | — | — |
| 5IED | Murine endoplasmic reticulum alpha-glucosidase II with castanospermine | x-ray diffraction | B | CA | — |
| 5IED | Murine endoplasmic reticulum alpha-glucosidase II with castanospermine | x-ray diffraction | B | — | — |
| 5IEE | Murine endoplasmic reticulum alpha-glucosidase II with 1-deoxynojirimycin | x-ray diffraction | B | CA | 2 (best 0.59) |
| 5IEE | Murine endoplasmic reticulum alpha-glucosidase II with 1- deoxynojirimycin | x-ray diffraction | B | — | — |
| 5IEF | Murine endoplasmic reticulum alpha-glucosidase II with N-butyl-1-deoxynojirimycin | x-ray diffraction | B | CA | 2 (best 0.59) |
| 5IEF | Murine endoplasmic reticulum alpha-glucosidase II with N-butyl-1- deoxynojirimycin | x-ray diffraction | B | — | — |
| 5IEG | Murine endoplasmic reticulum alpha-glucosidase II with N-9'-methoxynonyl-1-deoxynojirimycin. | x-ray diffraction | B | CA | 2 (best 0.60) |
| 5IEG | Murine endoplasmic reticulum alpha-glucosidase II with N-9'- methoxynonyl-1-deoxynojirimycin | x-ray diffraction | B | — | — |
| 7JTY | Co-crystal structure of alpha glucosidase with compound 1 | x-ray diffraction | B, D | CA | — |
| 7K9N | Co-crystal structure of alpha glucosidase with compound 2 | x-ray diffraction | B, D | CA | 4 (best 0.56) |
| 7K9N | Co-crystal structure of alpha glucosidase with compound 2 | x-ray diffraction | B, D | CA | — |
| 7K9O | Co-crystal structure of alpha glucosidase with compound 3 | x-ray diffraction | B, D | CA | — |
| 7K9Q | Co-crystal structure of alpha glucosidase with compound 4 | x-ray diffraction | B, D | SO4, CA | 4 (best 0.58) |
| 7K9Q | Co-crystal structure of alpha glucosidase with compound 4 | x-ray diffraction | B, D | SO4, CA | — |
| 7K9T | Co-crystal structure of alpha glucosidase with compound 5 | x-ray diffraction | B, D | CA | 4 (best 0.59) |
| 7K9T | Co-crystal structure of alpha glucosidase with compound 5 | x-ray diffraction | B, D | CA | — |
| 7KAD | Co-crystal structure of alpha glucosidase with compound 6 | x-ray diffraction | B, D | CA | 4 (best 0.60) |
| 7KAD | Co-crystal structure of alpha glucosidase with compound 6 | x-ray diffraction | B, D | CA | — |
| 7KB6 | Co-crystal structure of alpha glucosidase with compound 7 | x-ray diffraction | B, D | CA, SO4 | — |
| 7KB8 | Co-crystal structure of alpha glucosidase with compound 8 | x-ray diffraction | B, D | CA | 4 (best 0.57) |
| 7KB8 | Co-crystal structure of alpha glucosidase with compound 8 | x-ray diffraction | B, D | CA | — |
| 7KBJ | Co-crystal structure of alpha glucosidase with compound 9 | x-ray diffraction | B, D | SO4, CA | 5 (best 0.58) |
| 7KBJ | Co-crystal structure of alpha glucosidase with compound 9 | x-ray diffraction | B, D | SO4, CA | — |
| 7KBR | Co-crystal structure of alpha glucosidase with compound 10 | x-ray diffraction | B, D | CA, SO4 | 4 (best 0.57) |
| 7KBR | Co-crystal structure of alpha glucosidase with compound 10 | x-ray diffraction | B, D | CA, SO4 | — |
| 7KRY | Co-crystal structure of alpha glucosidase with compound 11 | x-ray diffraction | B, D | CA | 4 (best 0.58) |
| 7KRY | Co-crystal structure of alpha glucosidase with compound 11 | x-ray diffraction | B, D | CA | — |
| 7L9E | Crystal structure of apo-alpha glucosidase | x-ray diffraction | B, D | CA | 4 (best 0.59) |
| 7L9E | Crystal structure of apo-alpha glucosidase | x-ray diffraction | B, D | CA | — |
| O08795 | AlphaFold monomer V2.0 prediction for glucosidase 2 subunit beta (O08795) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7KBJ chain B against the predicted model O08795: TM-score 0.96, RMSD 0.64 Å
- 7KBJ chain B against the predicted model O08795: TM-score 0.96, RMSD 0.64 Å
- 7K9O chain B against the predicted model O08795: TM-score 0.96, RMSD 0.66 Å
- 5HJO chain B against the predicted model O08795: TM-score 0.96, RMSD 0.67 Å
- 5HJO chain B against the predicted model O08795: TM-score 0.96, RMSD 0.67 Å
- 7K9T chain B against the predicted model O08795: TM-score 0.96, RMSD 0.69 Å
- 7K9T chain B against the predicted model O08795: TM-score 0.96, RMSD 0.69 Å
- 7KB6 chain B against the predicted model O08795: TM-score 0.96, RMSD 0.69 Å
- 5HJR chain B against the predicted model O08795: TM-score 0.96, RMSD 0.71 Å
- 5HJR chain B against the predicted model O08795: TM-score 0.96, RMSD 0.71 Å
Elsewhere
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