UniProt O06662
tRNA(fMet)-specific endonuclease VapC (O06662)
tRNA(fMet)-specific endonuclease VapC (UniProt O06662), EC 3.1.-.-: 8 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O06662
- Protein
- tRNA(fMet)-specific endonuclease VapC
- EC
- 3.1.-.-
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
9 records of O06662 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3TND | Crystal structure of Shigella flexneri VapBC toxin-antitoxin complex | x-ray diffraction | A, C, E, G | — | — |
| 3TND | Crystal structure of shigella flexneri vapbc toxin-antitoxin complex | x-ray diffraction | A, C, E, G | — | — |
| 5ECD | Structure of the Shigella flexneri VapC mutant D98N crystal form 1 | x-ray diffraction | A, B | — | 1 (best 0.31) |
| 5ECD | Structure of the shigella flexneri vapc mutant D98N crystal form 1 | x-ray diffraction | A, B | — | — |
| 5ECW | Structure of the shigella flexneri vapc mutant D7A | x-ray diffraction | A, B | — | — |
| 5ECY | Structure of the shigella flexneri vapc mutant D98N crystal form 2 | x-ray diffraction | A, B, C, D, E, F, G, H | — | — |
| 5ED0 | Structure of the Shigella flexneri VapC mutant D7N | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| 5ED0 | Structure of the shigella flexneri vapc mutant D7N | x-ray diffraction | A, B, C, D, E, F, G, H, I, J, K, L | — | — |
| O06662 | AlphaFold monomer V2.0 prediction for TRNA(FMET)-specific endonuclease vapc (O06662) | predicted | A | — | 1 (best 0.34) |
Experiment against prediction
- 5ECY chain A against the predicted model O06662: TM-score 0.99, RMSD 0.38 Å
- 5ECD chain B against the predicted model O06662: TM-score 0.99, RMSD 0.41 Å
- 5ED0 chain A against the predicted model O06662: TM-score 0.99, RMSD 0.41 Å
- 5ED0 chain A against the predicted model O06662: TM-score 0.99, RMSD 0.41 Å
- 5ECD chain A against the predicted model O06662: TM-score 0.99, RMSD 0.42 Å
- 5ECD chain A against the predicted model O06662: TM-score 0.99, RMSD 0.42 Å
- 5ECW chain B against the predicted model O06662: TM-score 0.99, RMSD 0.46 Å
- 5ECW chain A against the predicted model O06662: TM-score 0.98, RMSD 0.66 Å
- 3TND chain A against the predicted model O06662: TM-score 0.96, RMSD 0.97 Å
- 3TND chain A against the predicted model O06662: TM-score 0.96, RMSD 0.97 Å
Elsewhere
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