UniProt O01583
Serine/threonine-protein kinase mrck-1 (O01583)
Serine/threonine-protein kinase mrck-1 (UniProt O01583), EC 2.7.11.1: 1 experimental structure and 1 predicted model on GenesisL1, 1 ligand bound, 35 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- O01583
- Protein
- Serine/threonine-protein kinase mrck-1
- EC
- 2.7.11.1
- Experimental structures
- 1
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 35 · 2 records with a druggable one
Structures
2 records of O01583 in the MolNFT archive: 1 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7Z6E | Structure of the C1-PH-CNH regulatory module of MRCK1 | x-ray diffraction | A, B, C, D, E | ZN | 20 (best 0.79) |
| O01583 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase mrck-1 (O01583) | predicted | A | — | 15 (best 0.77) |
Ligands
- ZN · Zinc ion · in 1 record
Experiment against prediction
- 7Z6E chain A against the predicted model O01583: TM-score 0.98, RMSD 1.19 Å
- 7Z6E chain C against the predicted model O01583: TM-score 0.98, RMSD 1.32 Å
- 7Z6E chain D against the predicted model O01583: TM-score 0.98, RMSD 1.45 Å
- 7Z6E chain B against the predicted model O01583: TM-score 0.97, RMSD 1.60 Å
- 7Z6E chain E against the predicted model O01583: TM-score 0.97, RMSD 1.58 Å
Elsewhere
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