UniProt O00512
B-cell CLL/lymphoma 9 protein (O00512)
B-cell CLL/lymphoma 9 protein (UniProt O00512): 15 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 15 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O00512
- Protein
- B-cell CLL/lymphoma 9 protein
- Experimental structures
- 15
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 15 · 1 record with a druggable one
Structures
16 records of O00512 in the MolNFT archive: 15 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2GL7 | Crystal Structure of a beta-catenin/BCL9/Tcf4 complex | x-ray diffraction | C, F | — | 1 (best 0.34) |
| 2GL7 | Crystal structure of a beta-CATENIN/BCL9/TCF4 complex | x-ray diffraction | C, F | — | 1 (best 0.34) |
| 2VP7 | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | x-ray diffraction | B | SO4 | — |
| 2VP7 | Decoding of methylated histone H3 tail by the pygo-BCL9 wnt signaling complex | x-ray diffraction | B | — | — |
| 2VPB | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | x-ray diffraction | B | — | — |
| 2VPB | Decoding of methylated histone H3 tail by the pygo-BCL9 wnt signaling complex | x-ray diffraction | B | — | — |
| 2VPD | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | x-ray diffraction | B, D | — | 2 (best 0.66) |
| 2VPD | Decoding of methylated histone H3 tail by the pygo-BCL9 wnt signaling complex | x-ray diffraction | B, D | — | — |
| 2VPE | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | x-ray diffraction | B, D | — | 3 (best 0.40) |
| 2VPE | Decoding of methylated histone H3 tail by the pygo-BCL9 wnt signaling complex | x-ray diffraction | B, D | — | — |
| 2VPG | Decoding of methylated histone H3 tail by the Pygo-BCL9 Wnt signaling complex | x-ray diffraction | B, D | — | 3 (best 0.43) |
| 2VPG | Decoding of methylated histone H3 tail by the pygo-BCL9 wnt signaling complex | x-ray diffraction | B, D | — | — |
| 3SL9 | X-ray structure of Beta catenin in complex with Bcl9 | x-ray diffraction | C, D, F, H | — | 5 (best 0.48) |
| 3SL9 | X-ray structure of beta catenin in complex with BCL9 | x-ray diffraction | C, D, F, H | — | — |
| 8Y0P | Beta-Catenin in complex with peptide 301 | x-ray diffraction | L | — | — |
| O00512 | AlphaFold monomer V2.0 prediction for B-cell CLL/LYMPHOMA 9 protein (O00512) | predicted | A | — | — |
Ligands
- SO4 · Sulfate ion · in 1 record
Experiment against prediction
- 3SL9 chain C against the predicted model O00512: TM-score 0.86, RMSD 0.45 Å
- 3SL9 chain C against the predicted model O00512: TM-score 0.86, RMSD 0.45 Å
- 3SL9 chain D against the predicted model O00512: TM-score 0.80, RMSD 1.43 Å
- 3SL9 chain D against the predicted model O00512: TM-score 0.80, RMSD 1.43 Å
- 3SL9 chain F against the predicted model O00512: TM-score 0.76, RMSD 0.88 Å
- 3SL9 chain F against the predicted model O00512: TM-score 0.76, RMSD 0.88 Å
- 2VPD chain B against the predicted model O00512: TM-score 0.74, RMSD 1.55 Å
- 2VPD chain B against the predicted model O00512: TM-score 0.74, RMSD 1.55 Å
- 2GL7 chain C against the predicted model O00512: TM-score 0.72, RMSD 0.51 Å
- 2GL7 chain C against the predicted model O00512: TM-score 0.72, RMSD 0.51 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.