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UniProt O00445

Synaptotagmin-5 (O00445)

Synaptotagmin-5 (UniProt O00445): 4 experimental structures and 1 predicted model on GenesisL1, 2 ligands bound, 3 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.

UniProt
O00445
Protein
Synaptotagmin-5
Experimental structures
4
Predicted models
1
Ligands
2
Pockets
3 · 1 record with a druggable one

Structures

5 records of O00445 in the MolNFT archive: 4 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
5H4YCrystal structure of human synaptotagmin 5 C2A domainx-ray diffractionACA—
5H4YCrystal structure of human synaptotagmin 5 C2A domainx-ray diffractionACA—
5H4ZCrystal structure of S202G mutant of human SYT-5 C2A domainx-ray diffractionA, BCA, CL1 (best 0.47)
5H4ZCrystal structure of S202G mutant of human syt-5 C2A domainx-ray diffractionA, BCA, CL1 (best 0.47)
O00445AlphaFold monomer V2.0 prediction for synaptotagmin-5 (O00445)predictedA—1 (best 0.69)

Ligands

  • CA · Calcium ion · in 4 records
  • CL · Chloride ion · in 2 records

Experiment against prediction

Elsewhere

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