UniProt O00425
Insulin-like growth factor 2 mRNA-binding protein 3 (O00425)
Insulin-like growth factor 2 mRNA-binding protein 3 (UniProt O00425): 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 10 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- O00425
- Protein
- Insulin-like growth factor 2 mRNA-binding protein 3
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 10 · 0 records with a druggable one
Structures
9 records of O00425 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6FQ1 | Crystal structure of the RRM12 domain of IMP3 | x-ray diffraction | A, B | — | 4 (best 0.43) |
| 6FQ1 | Crystal structure of the RRM12 domain of IMP3 | x-ray diffraction | A, B | — | — |
| 6FQR | Crystal structure of IMP3 RRM12 in complex with RNA (CCCC) | x-ray diffraction | A, B | — | 3 (best 0.48) |
| 6FQR | Crystal structure of IMP3 RRM12 in complex with RNA (cccc) | x-ray diffraction | A, B | — | — |
| 6GQE | X-ray structure of KH1-2 domain of IMP3 | x-ray diffraction | A | — | 1 (best 0.36) |
| 6GQE | X-ray structure of KH1-2 domain of IMP3 | x-ray diffraction | A | — | — |
| 6GX6 | Crystal structure of IMP3 RRM12 in complex with RNA (ACAC) | x-ray diffraction | A | PO4 | 2 (best 0.40) |
| 6GX6 | Crystal structure of IMP3 RRM12 in complex with RNA (acac) | x-ray diffraction | A | PO4 | — |
| O00425 | AlphaFold monomer V2.0 prediction for insulin-like growth factor 2 mRNA-binding protein 3 (O00425) | predicted | A | — | — |
Ligands
- PO4 · Phosphate ion · in 2 records
Experiment against prediction
- 6GQE chain A against the predicted model O00425: TM-score 0.95, RMSD 1.35 Å
- 6GQE chain A against the predicted model O00425: TM-score 0.95, RMSD 1.35 Å
- 6FQR chain A against the predicted model O00425: TM-score 0.54, RMSD 2.73 Å
- 6FQR chain A against the predicted model O00425: TM-score 0.54, RMSD 2.73 Å
- 6FQ1 chain B against the predicted model O00425: TM-score 0.53, RMSD 2.89 Å
- 6FQ1 chain B against the predicted model O00425: TM-score 0.53, RMSD 2.89 Å
- 6FQR chain B against the predicted model O00425: TM-score 0.53, RMSD 3.03 Å
- 6FQR chain B against the predicted model O00425: TM-score 0.53, RMSD 3.03 Å
- 6FQ1 chain A against the predicted model O00425: TM-score 0.53, RMSD 2.88 Å
- 6FQ1 chain A against the predicted model O00425: TM-score 0.53, RMSD 2.88 Å
Elsewhere
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