UniProt O00291
Huntingtin-interacting protein 1 (O00291)
Huntingtin-interacting protein 1 (UniProt O00291): 6 experimental structures and 1 predicted model on GenesisL1, 2 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O00291
- Protein
- Huntingtin-interacting protein 1
- Experimental structures
- 6
- Predicted models
- 1
- Pockets
- 2 · 0 records with a druggable one
Structures
7 records of O00291 in the MolNFT archive: 6 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2NO2 | Crystal structure of the DLLRKN-containing coiled-coil domain of Huntingtin-interacting protein 1 | x-ray diffraction | A | — | — |
| 2NO2 | Crystal structure of the dllrkn-containing coiled-coil domain of huntingtin-interacting protein 1 | x-ray diffraction | A | — | — |
| 2QA7 | Crystal structure of Huntingtin-interacting protein 1 (HIP1) coiled-coil domain with a basic… | x-ray diffraction | A, B, C, D | — | 1 (best 0.26) |
| 2QA7 | Crystal structure of huntingtin-interacting protein 1 (HIP1) coiled-coil domain with a basic… | x-ray diffraction | A, B, C, D | — | 1 (best 0.26) |
| 3I00 | Crystal Structure of the huntingtin interacting protein 1 coiled coil domain | x-ray diffraction | A, B | — | — |
| 3I00 | Crystal structure of the huntingtin interacting protein 1 coiled coil domain | x-ray diffraction | A, B | — | — |
| O00291 | AlphaFold monomer V2.0 prediction for huntingtin-interacting protein 1 (O00291) | predicted | A | — | — |
Experiment against prediction
- 2QA7 chain B against the predicted model O00291: TM-score 0.89, RMSD 1.23 Å
- 2QA7 chain B against the predicted model O00291: TM-score 0.89, RMSD 1.23 Å
- 3I00 chain A against the predicted model O00291: TM-score 0.87, RMSD 1.48 Å
- 3I00 chain A against the predicted model O00291: TM-score 0.87, RMSD 1.48 Å
- 3I00 chain B against the predicted model O00291: TM-score 0.81, RMSD 1.86 Å
- 3I00 chain B against the predicted model O00291: TM-score 0.81, RMSD 1.86 Å
- 2NO2 chain A against the predicted model O00291: TM-score 0.78, RMSD 2.24 Å
- 2NO2 chain A against the predicted model O00291: TM-score 0.78, RMSD 2.24 Å
- 2QA7 chain A against the predicted model O00291: TM-score 0.77, RMSD 2.26 Å
- 2QA7 chain A against the predicted model O00291: TM-score 0.77, RMSD 2.26 Å
Elsewhere
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