UniProt O00170
AH receptor-interacting protein (O00170)
AH receptor-interacting protein (UniProt O00170): 8 experimental structures and 1 predicted model on GenesisL1, 8 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- O00170
- Protein
- AH receptor-interacting protein
- Experimental structures
- 8
- Predicted models
- 1
- Pockets
- 8 · 2 records with a druggable one
Structures
9 records of O00170 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2LKN | Solution structure of the PPIase domain of human aryl-hydrocarbon receptor-interacting protein (AIP) | solution nmr | A | — | — |
| 2LKN | Solution structure of the ppiase domain of human aryl-hydrocarbon receptor-interacting protein (aip) | solution nmr | A | — | — |
| 4AIF | AIP TPR domain in complex with human Hsp90 peptide | x-ray diffraction | A, B | — | — |
| 4AIF | Aip tpr domain in complex with human HSP90 peptide | x-ray diffraction | A, B | — | — |
| 4APO | AIP TPR domain in complex with human Tomm20 peptide | x-ray diffraction | A, B | — | — |
| 4APO | Aip tpr domain in complex with human TOMM20 peptide | x-ray diffraction | A, B | — | — |
| 7ZUB | Cryo-EM structure of the indirubin-bound Hsp90-XAP2-AHR complex | electron microscopy | C | — | 5 (best 0.73) |
| 8QMO | Cryo-EM structure of the benzo[a]pyrene-bound Hsp90-XAP2-AHR complex | electron microscopy | C | — | 3 (best 0.78) |
| O00170 | AlphaFold monomer V2.0 prediction for ah receptor-interacting protein (O00170) | predicted | A | — | — |
Experiment against prediction
- 4AIF chain B against the predicted model O00170: TM-score 0.98, RMSD 0.60 Å
- 4AIF chain B against the predicted model O00170: TM-score 0.98, RMSD 0.60 Å
- 4APO chain A against the predicted model O00170: TM-score 0.98, RMSD 0.63 Å
- 4APO chain A against the predicted model O00170: TM-score 0.98, RMSD 0.63 Å
- 4AIF chain A against the predicted model O00170: TM-score 0.98, RMSD 0.70 Å
- 4AIF chain A against the predicted model O00170: TM-score 0.98, RMSD 0.70 Å
- 4APO chain B against the predicted model O00170: TM-score 0.96, RMSD 1.02 Å
- 4APO chain B against the predicted model O00170: TM-score 0.96, RMSD 1.02 Å
- 8QMO chain C against the predicted model O00170: TM-score 0.92, RMSD 2.01 Å
- 7ZUB chain C against the predicted model O00170: TM-score 0.92, RMSD 2.04 Å
Elsewhere
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