UniProt O00141
Serine/threonine-protein kinase Sgk1 (O00141)
Serine/threonine-protein kinase Sgk1 (UniProt O00141), EC 2.7.11.1: 9 experimental structures on GenesisL1, 1 ligand bound, 1 pocket. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- O00141
- Protein
- Serine/threonine-protein kinase Sgk1
- EC
- 2.7.11.1
- Experimental structures
- 9
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 1 · 1 record with a druggable one
Structures
9 records of O00141 in the MolNFT archive: 9 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2R5T | Crystal Structure of Inactive Serum and Glucocorticoid- Regulated Kinase 1 in Complex with AMP-PNP | x-ray diffraction | A | — | — |
| 2R5T | Crystal structure of inactive serum and glucocorticoid- regulated kinase 1 in complex with AMP-pnp | x-ray diffraction | A | — | — |
| 3HDM | Crystal structure of serum and glucocorticoid-regulated kinase 1 in complex with compound 1 | x-ray diffraction | A | — | — |
| 3HDM | Crystal structure of serum and glucocorticoid-regulated kinase 1 in complex with compound 1 | x-ray diffraction | A | — | — |
| 3HDN | Crystal structure of serum and glucocorticoid-regulated kinase 1 in complex with compound 2 | x-ray diffraction | A | — | — |
| 3HDN | Crystal structure of serum and glucocorticoid-regulated kinase 1 in complex with compound 2 | x-ray diffraction | A | — | — |
| 7PUE | Human serum and glucocorticoid-regulated kinase 1 in complex with pyrazolopyridine inhibitor 3a | x-ray diffraction | A | 86H | 1 (best 0.73) |
| 7PUE | Human serum and glucocorticoid-regulated kinase 1 in complex with pyrazolopyridine inhibitor 3A | x-ray diffraction | A | 86H | — |
| O00141 | AlphaFold monomer V2.0 prediction for SERINE/THREONINE-protein kinase SGK1 (O00141) | — | — | — |
Ligands
- 86H · 6-[4-[[2,3-bis(chloranyl)phenyl]sulfonylamino]phenyl]-~{N}-[(3~{R})-pyrrolidin-3-yl]-2~{H}-pyrazolo[3,4-b]pyridine-4-carboxamide · in 2 records
Elsewhere
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