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Ligand · 86H

86H · 6-[4-[[2,3-bis(chloranyl)phenyl]sulfonylamino]phenyl]-~{N}-[(3~{R})-pyrrolidin-3-yl]-2~{H}-pyrazolo[3,4-b]pyridine-4-carboxamide

86H, 6-[4-[[2,3-bis(chloranyl)phenyl]sulfonylamino]phenyl]-~{N}-[(3~{R})-pyrrolidin-3-yl]-2~{H}-pyrazolo[3,4-b]pyridine-4-carboxamide (C23 H20 Cl2 N6 O3 S, 531.4 g/mol), in the MolNFT structures on GenesisL1: bound in 2 records (1 PDB…

Component
86H
Formula
C23 H20 Cl2 N6 O3 S
Class
ligand
Structures
2
PDB entries
1

Binding sites

86H in 2 structures; the first of them:

  • 7PUE · Human serum and glucocorticoid-regulated kinase 1 in complex with pyrazolopyridine… · 86H A503 · binds ILE104, GLY105, VAL112, ALA125, LYS127, LYS152, VAL160, LEU162 and 14 more
  • 7PUE · Human serum and glucocorticoid-regulated kinase 1 in complex with pyrazolopyridine… · 86H A503 · binds ILE104, GLY105, VAL112, ALA125, LYS127, VAL160, LEU162, PHE174 and 13 more

Residues it binds most

LEU 2, ASP 2, GLU 2, GLY 2, ILE 2, PHE 2, VAL 2, LYS 2, ALA 2, CYS 2 (residue and the binding sites it lines).

Found with

  • GOL · Glycerol

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