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UniProt M1H2Q1

Hyaluronan synthase (M1H2Q1)

Hyaluronan synthase (UniProt M1H2Q1): 13 experimental structures on GenesisL1, 8 ligands bound, 60 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
M1H2Q1
Protein
Hyaluronan synthase
Experimental structures
13
Predicted models
0
Ligands
8
Pockets
60 · 8 records with a druggable one

Structures

13 records of M1H2Q1 in the MolNFT archive: 13 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
7SP6Chlorella virus hyaluronan synthaseelectron microscopyAY01, MN, 3PE6 (best 0.88)
7SP6Chlorella virus hyaluronan synthaseelectron microscopyAY01, MN, 3PE—
7SP7Chlorella virus hyaluronan synthase inhibited by UDPelectron microscopyA3PE, Y01, UDP, MN8 (best 0.88)
7SP7Chlorella virus hyaluronan synthase inhibited by udpelectron microscopyA3PE, Y01, UDP, MN—
7SP8Chlorella virus Hyaluronan Synthase bound to UDP-GlcNAcelectron microscopyAUD1, 3PE, Y01, MN9 (best 0.88)
7SP8Chlorella virus hyaluronan synthase bound to udp-glcnacelectron microscopyAUD1, 3PE, Y01, MN—
7SP9Chlorella virus Hyaluronan Synthase in the GlcNAc-primed channel-closed stateelectron microscopyANAG, Y017 (best 0.88)
7SP9Chlorella virus hyaluronan synthase in the glcnac-primed channel- closed stateelectron microscopyANAG, Y01—
7SPAChlorella virus Hyaluronan Synthase in the GlcNAc-primed, channel-open stateelectron microscopyANAG, Y01, 3PE10 (best 0.87)
7SPAChlorella virus hyaluronan synthase in the glcnac-primed, channel-open stateelectron microscopyANAG, Y01, 3PE—
8SNCChlorella virus Hyaluronan Synthase bound to GlcA extended GlcNAc primerelectron microscopyANAG, BDP, Y01, MN7 (best 0.86)
8SNDChlorella virus Hyaluronan Synthase bound to GlcNAc primer and UDP-GlcAelectron microscopyA3PE, NAG, UGA, Y01, MN8 (best 0.87)
8SNEChlorella virus Hyaluronan Synthase bound to GlcA extended GlcNAc primer and UDPelectron microscopyANAG, BDP, UDP, Y01, 3PE, MN5 (best 0.87)

Ligands

  • Y01 · Cholesterol hemisuccinate · in 13 records
  • 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · in 10 records
  • MN · Manganese (II) ion · in 9 records
  • NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · in 7 records
  • UDP · Uridine-5'-diphosphate · in 3 records
  • BDP · beta-D-glucopyranuronic acid · in 2 records
  • UD1 · Uridine-diphosphate-N-acetylglucosamine · in 2 records
  • UGA · Uridine-5'-diphosphate-glucuronic acid · in 1 record

Elsewhere

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