UniProt K7NTP5
Heat shock protein 70 (K7NTP5)
Heat shock protein 70 (UniProt K7NTP5): 17 experimental structures on GenesisL1, 14 ligands bound, 36 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- K7NTP5
- Protein
- Heat shock protein 70
- Experimental structures
- 17
- Predicted models
- 0
- Ligands
- 14
- Pockets
- 36 · 6 records with a druggable one
Structures
17 records of K7NTP5 in the MolNFT archive: 17 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6RZQ | Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain - ANP-PnP bound state | x-ray diffraction | A, B | MG, ANP | 4 (best 0.80) |
| 6RZQ | Plasmodium falciparum HSP70-X chaperone nucleotide binding domain - anp-pnp bound state | x-ray diffraction | A, B | MG, ANP | — |
| 6S02 | Plasmodium falciparum HSP70-X chaperone nucleotide binding domain - ADP bound state | x-ray diffraction | A, B | ADP, MG | — |
| 6ZHI | Structure of the Plasmodium falciparum Hsp70-x substrate binding domain in complex with hydrophobic… | x-ray diffraction | A, B, C, D | — | 15 (best 0.77) |
| 6ZHI | Structure of the plasmodium falciparum HSP70-X substrate binding domain in complex with hydrophobic… | x-ray diffraction | A, B, C, D | — | — |
| 7NQR | Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z287256168 | x-ray diffraction | A, B | AN2, PO4, CL, SYQ | 4 (best 0.79) |
| 7NQR | Plasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with Z287256168 | x-ray diffraction | A, B | AN2, PO4, CL, SYQ | — |
| 7NQS | Plasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with Z1203107138 | x-ray diffraction | A, B | AN2, PO4, JH1 | — |
| 7NQU | Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z396380540 | x-ray diffraction | A, B | AN2, PO4, CL, HR5 | 5 (best 0.79) |
| 7NQU | Plasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with Z396380540 | x-ray diffraction | A, B | AN2, PO4, CL, HR5 | — |
| 7NQZ | Plasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with Z1827898537 | x-ray diffraction | A, B | AN2, PO4, CL, WM7 | — |
| 7OOE | Plasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with Z321318226 | x-ray diffraction | A, B | AN2, JHJ, PO4, CL | — |
| 7OOG | Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023823 | x-ray diffraction | A, B | AN2, HEW, PO4, CL, MG | 4 (best 0.79) |
| 7OOG | Plasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with ncl-00023823 | x-ray diffraction | A, B | AN2, HEW, PO4, CL, MG | — |
| 7OOH | Plasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with ncl-00023818 | x-ray diffraction | A, B | AN2, PYZ, PO4, CL, IOD | — |
| 7P31 | Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818 | x-ray diffraction | A, B | AN2, PYZ, PO4, CL, IOD | 4 (best 0.80) |
| 7P31 | Plasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with ncl-00023818 | x-ray diffraction | A, B | AN2, PYZ, PO4, CL, IOD | — |
Ligands
- AN2 · Amp phosphoramidate · in 12 records
- PO4 · Phosphate ion · in 12 records
- CL · Chloride ion · in 11 records
- MG · Magnesium ion · in 5 records
- IOD · Iodide ion · in 3 records
- PYZ · 4-iodopyrazole · in 3 records
- ANP · Phosphoaminophosphonic acid-adenylate ester · in 2 records
- HEW · 4-bromanylpyridin-2-amine · in 2 records
- HR5 · ~{N}-(cyclobutylmethyl)-1,5-dimethyl-pyrazole-4-carboxamide · in 2 records
- SYQ · (S)-N-(1-cyclopropylethyl)-6-methylpicolinamide · in 2 records
- ADP · Adenosine-5'-diphosphate · in 1 record
- JH1 · 1-ethyl-N-[(4-fluorophenyl)methyl]-1H-pyrazole-4-carboxamide · in 1 record
- JHJ · N-(4-methoxyphenyl)-N'-pyridin-4-ylurea · in 1 record
- WM7 · (3S)-N-benzylpyrrolidin-3-amine · in 1 record
Elsewhere
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