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UniProt K7NTP5

Heat shock protein 70 (K7NTP5)

Heat shock protein 70 (UniProt K7NTP5): 17 experimental structures on GenesisL1, 14 ligands bound, 36 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
K7NTP5
Protein
Heat shock protein 70
Experimental structures
17
Predicted models
0
Ligands
14
Pockets
36 · 6 records with a druggable one

Structures

17 records of K7NTP5 in the MolNFT archive: 17 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6RZQPlasmodium falciparum Hsp70-x chaperone nucleotide binding domain - ANP-PnP bound statex-ray diffractionA, BMG, ANP4 (best 0.80)
6RZQPlasmodium falciparum HSP70-X chaperone nucleotide binding domain - anp-pnp bound statex-ray diffractionA, BMG, ANP—
6S02Plasmodium falciparum HSP70-X chaperone nucleotide binding domain - ADP bound statex-ray diffractionA, BADP, MG—
6ZHIStructure of the Plasmodium falciparum Hsp70-x substrate binding domain in complex with hydrophobic…x-ray diffractionA, B, C, D—15 (best 0.77)
6ZHIStructure of the plasmodium falciparum HSP70-X substrate binding domain in complex with hydrophobic…x-ray diffractionA, B, C, D——
7NQRPlasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z287256168x-ray diffractionA, BAN2, PO4, CL, SYQ4 (best 0.79)
7NQRPlasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with Z287256168x-ray diffractionA, BAN2, PO4, CL, SYQ—
7NQSPlasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with Z1203107138x-ray diffractionA, BAN2, PO4, JH1—
7NQUPlasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with Z396380540x-ray diffractionA, BAN2, PO4, CL, HR55 (best 0.79)
7NQUPlasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with Z396380540x-ray diffractionA, BAN2, PO4, CL, HR5—
7NQZPlasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with Z1827898537x-ray diffractionA, BAN2, PO4, CL, WM7—
7OOEPlasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with Z321318226x-ray diffractionA, BAN2, JHJ, PO4, CL—
7OOGPlasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023823x-ray diffractionA, BAN2, HEW, PO4, CL, MG4 (best 0.79)
7OOGPlasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with ncl-00023823x-ray diffractionA, BAN2, HEW, PO4, CL, MG—
7OOHPlasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with ncl-00023818x-ray diffractionA, BAN2, PYZ, PO4, CL, IOD—
7P31Plasmodium falciparum Hsp70-x chaperone nucleotide binding domain in complex with NCL-00023818x-ray diffractionA, BAN2, PYZ, PO4, CL, IOD4 (best 0.80)
7P31Plasmodium falciparum HSP70-X chaperone nucleotide binding domain in complex with ncl-00023818x-ray diffractionA, BAN2, PYZ, PO4, CL, IOD—

Ligands

  • AN2 · Amp phosphoramidate · in 12 records
  • PO4 · Phosphate ion · in 12 records
  • CL · Chloride ion · in 11 records
  • MG · Magnesium ion · in 5 records
  • IOD · Iodide ion · in 3 records
  • PYZ · 4-iodopyrazole · in 3 records
  • ANP · Phosphoaminophosphonic acid-adenylate ester · in 2 records
  • HEW · 4-bromanylpyridin-2-amine · in 2 records
  • HR5 · ~{N}-(cyclobutylmethyl)-1,5-dimethyl-pyrazole-4-carboxamide · in 2 records
  • SYQ · (S)-N-(1-cyclopropylethyl)-6-methylpicolinamide · in 2 records
  • ADP · Adenosine-5'-diphosphate · in 1 record
  • JH1 · 1-ethyl-N-[(4-fluorophenyl)methyl]-1H-pyrazole-4-carboxamide · in 1 record
  • JHJ · N-(4-methoxyphenyl)-N'-pyridin-4-ylurea · in 1 record
  • WM7 · (3S)-N-benzylpyrrolidin-3-amine · in 1 record

Elsewhere

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