UniProt K7GR43

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (K7GR43)

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1 (UniProt K7GR43): 55 experimental structures on GenesisL1, 3 ligands bound, 61 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: K7GR43
Protein: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 1
Experimental structures: 55
Predicted models: 0
Ligands: 3
Pockets: 61 · 35 records with a druggable one

Structures

55 records of K7GR43 in the MolNFT archive: 55 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
5GPN	Architecture of mammalian respirasome	electron microscopy	Ac	—	—
5GUP	Cryo-EM structure of mammalian respiratory supercomplex I1III2IV1	electron microscopy	S	PEE	2 (best 0.90)
7V2C	Active state complex I from Q10 dataset	electron microscopy	S	PLX, CDL, PEE	2 (best 0.85)
7V2C	Active state complex I from Q10 dataset	electron microscopy	S	PLX, CDL, PEE	—
7V2D	Deactive state complex I from Q10 dataset	electron microscopy	S	CDL, PEE	1 (best 0.91)
7V2D	Deactive state complex I from Q10 dataset	electron microscopy	S	CDL, PEE	—
7V2E	Active state complex I from Q10-NADH dataset	electron microscopy	S	CDL, PEE	1 (best 0.91)
7V2E	Active state complex I from Q10-NADH dataset	electron microscopy	S	CDL, PEE	—
7V2F	Deactive state complex I from Q10-NADH dataset	electron microscopy	S	CDL, PEE	2 (best 0.90)
7V2F	Deactive state complex I from Q10-NADH dataset	electron microscopy	S	CDL, PEE	—
7V2H	Active state complex I from DQ-NADH dataset	electron microscopy	S	CDL, PEE	2 (best 0.89)
7V2H	Active state complex I from dq-NADH dataset	electron microscopy	S	CDL, PEE	—
7V2K	Deactive state complex I from DQ-NADH dataset	electron microscopy	S	CDL, PEE	2 (best 0.88)
7V2K	Deactive state complex I from dq-NADH dataset	electron microscopy	S	CDL, PEE	—
7V2R	Active state complex I from Q1-NADH dataset	electron microscopy	S	CDL, PEE	2 (best 0.89)
7V2R	Active state complex I from Q1-NADH dataset	electron microscopy	S	CDL, PEE	—
7V30	Deactive state complex I from Q1-NADH dataset	electron microscopy	S	CDL, PEE	1 (best 0.91)
7V30	Deactive state complex I from Q1-NADH dataset	electron microscopy	S	CDL, PEE	—
7V31	Active state complex I from rote dataset	electron microscopy	S	CDL, PEE	2 (best 0.90)
7V31	Active state complex I from rotenone dataset	electron microscopy	S	CDL, PEE	—
7V32	Deactive state complex I from rotenone dataset	electron microscopy	S	CDL, PEE	—
7V33	Active state complex I from rote -NADH dataset	electron microscopy	S	CDL, PEE	2 (best 0.86)
7V33	Active state complex I from rotenone-NADH dataset	electron microscopy	S	CDL, PEE	—
7V3M	Deactive state complex I from rote -NADH dataset	electron microscopy	S	CDL, PEE	—
7V3M	Deactive state complex I from rotenone-NADH dataset	electron microscopy	S	CDL, PEE	—
7VBL	Membrane arm of active state ci from dq-NADH dataset	electron microscopy	S	PEE	—
7VBP	Membrane arm of deactive state CI from DQ-NADH dataset	electron microscopy	S	PEE	—
7VBP	Membrane arm of deactive state ci from dq-NADH dataset	electron microscopy	S	PEE	—
7VC0	Membrane arm of active state ci from rotenone-NADH dataset	electron microscopy	S	PEE	—
7VWL	Membrane arm of deactive state CI from rote -NADH dataset	electron microscopy	S	PEE	2 (best 0.90)
7VWL	Membrane arm of deactive state ci from rotenone-NADH dataset	electron microscopy	S	PEE	—
7VXS	Membrane arm of active state CI from Q10 dataset	electron microscopy	S	PEE	3 (best 0.84)
7VY1	Membrane arm of deactive state CI from Q10 dataset	electron microscopy	S	PEE	2 (best 0.89)
7VYE	Membrane arm of deactive state CI from Q10-NADH dataset	electron microscopy	S	PEE	2 (best 0.89)
7VYS	Membrane arm of active state CI from Q1-NADH dataset	electron microscopy	S	PEE	1 (best 0.90)
7VZW	Active state CI from Q10 dataset, Subclass 2	electron microscopy	S	CDL, PLX, PEE	1 (best 0.91)
7W0H	Deactive state CI from Q10 dataset, Subclass 2	electron microscopy	S	CDL, PEE	2 (best 0.89)
7W1O	Deactive state CI from Q10-NADH dataset, Subclass 1	electron microscopy	S	PEE	2 (best 0.89)
7W1T	Active state CI from Rote dataset, Subclass 1	electron microscopy	S	CDL, PEE	2 (best 0.90)
7W1U	Active state CI from Rote dataset, Subclass 2	electron microscopy	S	CDL, PEE	2 (best 0.82)
7W1V	Active state CI from Rote -NADH dataset, Subclass 1	electron microscopy	S	CDL, PEE	3 (best 0.89)
7W20	Active state CI from Rote -NADH dataset, Subclass 3	electron microscopy	S	CDL, PEE	1 (best 0.87)
7W2K	Deactive state CI from Rote -NADH dataset, Subclass 1	electron microscopy	S	PEE	2 (best 0.90)
7W2L	Deactive state CI from Rote -NADH dataset, Subclass 2	electron microscopy	S	CDL, PEE	1 (best 0.91)
7W2R	Active state CI from DQ-NADH dataset, Subclass 1	electron microscopy	S	CDL, PEE	1 (best 0.87)
7W2U	Active state CI from DQ-NADH dataset, Subclass 2	electron microscopy	S	CDL, PEE	2 (best 0.82)
7W2Y	Active state CI from DQ-NADH dataset, Subclass 3	electron microscopy	S	CDL, PEE	2 (best 0.82)
7W32	Deactive state CI from DQ-NADH dataset, Subclass 2	electron microscopy	S	CDL, PEE	2 (best 0.90)
7W35	Deactive state CI from DQ-NADH dataset, Subclass 3	electron microscopy	S	PEE	2 (best 0.89)
7W4C	Active state CI from Q1-NADH dataset, Subclass 1	electron microscopy	S	CDL, PEE	1 (best 0.84)
7W4E	Active state CI from Q1-NADH dataset, Subclass 3	electron microscopy	S	CDL, PEE	1 (best 0.82)
7W4G	Active state CI from Q1-NADH dataset, Subclass 5	electron microscopy	S	CDL, PEE	2 (best 0.86)
7W4J	Deactive state CI from Q1-NADH dataset, Subclass 1	electron microscopy	S	CDL, PEE	—
7W4N	Deactive state CI from Q1-NADH dataset, Subclass 5	electron microscopy	S	CDL, PEE	1 (best 0.91)
7W4Q	Deactive state CI from Q1-NADH dataset, Subclass 6	electron microscopy	S	CDL, PEE	2 (best 0.90)

Ligands

PEE · 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine · in 54 records
CDL · Cardiolipin · in 40 records
PLX · (9R,11S)-9-({[(1S)-1-hydroxyhexadecyl]oxy}methyl)-2,2-dimethyl-5,7,10-trioxa-2lambda~5~-aza-6lambda~5~-phosphaoctacosane-6,6,11-triol · in 3 records

Elsewhere

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.