UniProt J9VFT1
Acetyl-coenzyme A synthetase (J9VFT1)
Acetyl-coenzyme A synthetase (UniProt J9VFT1), EC 6.2.1.1: 18 experimental structures on GenesisL1, 10 ligands bound, 158 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- J9VFT1
- Protein
- Acetyl-coenzyme A synthetase
- EC
- 6.2.1.1
- Experimental structures
- 18
- Predicted models
- 0
- Ligands
- 10
- Pockets
- 158 · 9 records with a druggable one
Structures
18 records of J9VFT1 in the MolNFT archive: 18 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5IFI | Crystal structure of acetyl-CoA synthetase in complex with adenosine-5'-propylphosphate from… | x-ray diffraction | A, B, C | PRX, PO4 | 18 (best 0.89) |
| 5IFI | Crystal structure of acetyl-CoA synthetase in complex with adenosine- 5'-propylphosphate from… | x-ray diffraction | A, B, C | — | — |
| 5K85 | Crystal Structure of Acetyl-CoA Synthetase in Complex with Adenosine-5'-propylphosphate and… | x-ray diffraction | A, B, C | PRX, PO4, COA | 20 (best 0.88) |
| 5K85 | Crystal structure of acetyl-CoA synthetase in complex with adenosine- 5'-propylphosphate and… | x-ray diffraction | A, B, C | PRX, PO4, COA | — |
| 5K8F | Crystal structure of Acetyl-CoA Synthetase in complex with ATP and Acetyl-AMP from Cryptococcus… | x-ray diffraction | A, B, C | ATP, 6R9, MG, PO4 | — |
| 5K8F | Crystal structure of acetyl-CoA synthetase in complex with ATP and acetyl-AMP from cryptococcus… | x-ray diffraction | A, B, C | ATP, 6R9, MG, PO4 | — |
| 5U29 | Crystal structure of Cryptococcus neoformans H99 Acetyl-CoA Synthetase in complex with Ac-AMS | x-ray diffraction | A, B, C | 7RM, PO4 | 20 (best 0.89) |
| 5U29 | Crystal structure of cryptococcus neoformans H99 acetyl-CoA synthetase in complex with ac-ams | x-ray diffraction | A, B, C | 7RM, PO4 | — |
| 5VPV | Crystal structure of Apo Cryptococcus neoformans H99 Acetyl-CoA Synthetase with an Acetylated… | x-ray diffraction | A, B, C | PO4 | 15 (best 0.88) |
| 5VPV | Crystal structure of apo cryptococcus neoformans H99 acetyl-CoA synthetase with an acetylated… | x-ray diffraction | A, B, C | PO4 | — |
| 7KNO | Crystal structure of Acetyl-CoA synthetase in complex with adenosine-5'-ethylphosphate from… | x-ray diffraction | A, B, C | WTA, PO4 | 20 (best 0.89) |
| 7KNO | Crystal structure of acetyl-CoA synthetase in complex with adenosine- 5'-ethylphosphate from… | x-ray diffraction | A, B, C | WTA, PO4 | — |
| 7KNP | Crystal structure of Acetyl-CoA synthetase in complex with adenosine-5'-butylphosphate from… | x-ray diffraction | A, B, C | WT7, PO4 | 18 (best 0.88) |
| 7KNP | Crystal structure of acetyl-CoA synthetase in complex with adenosine- 5'-butylphosphate from… | x-ray diffraction | A, B, C | WT7, PO4 | — |
| 7L4G | Crystal Structure of Acetyl-CoA synthetase in complex with acetyl adenylate from Cryptococcus… | x-ray diffraction | A, B, C | 6R9, PO4, K | 20 (best 0.89) |
| 7L4G | Crystal structure of acetyl-CoA synthetase in complex with acetyl adenylate from cryptococcus… | x-ray diffraction | A, B, C | 6R9, PO4, K | — |
| 9C8R | CryoEM structure of Apo Cryptococcus neoformans H99 Acetyl-CoA Synthetase | electron microscopy | A, B, C | — | 13 (best 0.88) |
| 9C8S | CryoEM structure of Cryptococcus neoformans H99 Acetyl-CoA Synthetase in complex with… | electron microscopy | A, B, C | WTA | 14 (best 0.89) |
Ligands
- PO4 · Phosphate ion · in 15 records
- 6R9 · [[(2~{R},3~{S},4~{R},5~{R})-5-(6-aminopurin-9-yl)-3,4-bis(oxidanyl)oxolan-2-yl]methoxy-oxidanyl-phosphoryl] ethanoate · in 4 records
- PRX · Adenosine-5'-monophosphate-propyl ester · in 3 records
- WTA · 5'-O-[(S)-ethoxy(hydroxy)phosphoryl]adenosine · in 3 records
- 7RM · 5'-O-(acetylsulfamoyl)adenosine · in 2 records
- ATP · Adenosine-5'-triphosphate · in 2 records
- COA · Coenzyme A · in 2 records
- K · Potassium ion · in 2 records
- MG · Magnesium ion · in 2 records
- WT7 · 5'-O-[(S)-butoxy(hydroxy)phosphoryl]adenosine · in 2 records
Elsewhere
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