UniProt I0B503
Methylthioadenosine phosphorylase (I0B503)
Methylthioadenosine phosphorylase (UniProt I0B503), EC 2.4.2.28: 26 experimental structures on GenesisL1, 5 ligands bound, 108 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- I0B503
- Protein
- Methylthioadenosine phosphorylase
- EC
- 2.4.2.28
- Experimental structures
- 26
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 108 · 6 records with a druggable one
Structures
26 records of I0B503 in the MolNFT archive: 26 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 4L5A | Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with tubercidin | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4L5A | Methylthioadenosine phosphorylase from schistosoma mansoni in complex with tubercidin | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4L5C | Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with adenine in space group… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4L5C | Methylthioadenosine phosphorylase from schistosoma mansoni in complex with adenine in space group… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4L5Y | Methylthioadenosine phosphorylase from Schistosoma mansoni in APO form | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4L5Y | Methylthioadenosine phosphorylase from schistosoma mansoni in apo form | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4L6I | Methylthioadenosine phosphorylase from Schistosoma mansoni in complex with adenine | x-ray diffraction | A, B, C, D, E, F | — | — |
| 4L6I | Methylthioadenosine phosphorylase from schistosoma mansoni in complex with adenine | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5F73 | Crystal structure of Mutant S12T of Adenosine/Methylthioadenosine Phosphorylase in APO form | x-ray diffraction | A, B, C, D, E, F | SO4 | 20 (best 0.86) |
| 5F73 | Crystal structure of mutant S12T of ADENOSINE/METHYLTHIOADENOSINE phosphorylase in apo form | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5F76 | Crystal structure of Mutant S12T of Adenosine/Methylthioadenosine Phosphorylase from Schistosoma… | x-ray diffraction | A, B, C | MTA, SO4 | — |
| 5F76 | Crystal structure of mutant S12T of ADENOSINE/METHYLTHIOADENOSINE phosphorylase from schistosoma… | x-ray diffraction | A, B, C | — | — |
| 5F77 | Crystal structure of Mutant S12T of adenosine/Methylthioadenosine phosphorylase from Schistosoma… | x-ray diffraction | A, B, C | ADE, SO4 | — |
| 5F77 | Crystal structure of mutant S12T of ADENOSINE/METHYLTHIOADENOSINE phosphorylase from schistosoma… | x-ray diffraction | A, B, C | — | — |
| 5F78 | Crystal structure of Mutant N87T of adenosine/Methylthioadenosine phosphorylase from Schistosoma… | x-ray diffraction | A, B, C, D, E, F | SO4 | 20 (best 0.86) |
| 5F78 | Crystal structure of mutant N87T of ADENOSINE/METHYLTHIOADENOSINE phosphorylase from schistosoma… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5F7J | Crystal structure of Mutant N87T of adenosine/Methylthioadenosine phosphorylase from Schistosoma… | x-ray diffraction | A, B, C, D, E, F | ADE, PO4 | 20 (best 0.86) |
| 5F7J | Crystal structure of mutant N87T of ADENOSINE/METHYLTHIOADENOSINE phosphorylase from schistosoma… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5F7O | Crystal structure of Mutant Q289L of adenosine/Methylthioadenosine phosphorylase from Schistosoma… | x-ray diffraction | A, B, C | ADE, SO4 | 15 (best 0.86) |
| 5F7O | Crystal structure of mutant Q289L of ADENOSINE/METHYLTHIOADENOSINE phosphorylase from schistosoma… | x-ray diffraction | A, B, C | — | — |
| 5F7X | Crystal structure of Mutant Q289L of adenosine/Methylthioadenosine phosphorylase from Schistosoma… | x-ray diffraction | A, B, C | TBN, SO4 | 13 (best 0.85) |
| 5F7X | Crystal structure of mutant Q289L of ADENOSINE/METHYLTHIOADENOSINE phosphorylase from schistosoma… | x-ray diffraction | A, B, C | — | — |
| 5F7Z | Crystal structure of Double Mutant S12T and N87T of Adenosine/Methylthioadenosine Phosphorylase… | x-ray diffraction | A, B, C, D, E, F | PO4 | — |
| 5F7Z | Crystal structure of double mutant S12T and N87T of ADENOSINE/METHYLTHIOADENOSINE phosphorylase… | x-ray diffraction | A, B, C, D, E, F | — | — |
| 5FAK | Crystal structure of Double Mutant S12T and N87T of Adenosine/Methylthioadenosine Phosphorylase… | x-ray diffraction | A, B, C, D, E, F | ADE, SO4 | 20 (best 0.84) |
| 5FAK | Crystal structure of double mutant S12T and N87T of ADENOSINE/METHYLTHIOADENOSINE phosphorylase… | x-ray diffraction | A, B, C, D, E, F | — | — |
Ligands
Elsewhere
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