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Ligand · TBN

TBN · 2-(4-amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol

TBN, 2-(4-amino-pyrrolo[2,3-d]pyrimidin-7-yl)-5-hydroxymethyl-tetrahydro-furan-3,4-diol (C11 H14 N4 O4, 266.3 g/mol), in the MolNFT structures on GenesisL1: bound in 4 records (4 PDB entries). Every binding site with its residues within…

Component
TBN
Formula
C11 H14 N4 O4
Class
ligand
Structures
4
PDB entries
4

Binding sites

TBN in 4 structures; the first of them:

  • 5F7X · Crystal structure of Mutant Q289L of adenosine/Methylthioadenosine phosphorylase from… · TBN A301 · binds SER12, HIS55, PRO63, ALA88, CYS89, GLY90, ILE182, PHE187 and 11 more
  • 8BSD · SARS-CoV-2 nsp10-16 methyltransferase in complex with tubercidin · TBN A7220 · binds GLY6869, GLY6871, ASP6897, LEU6898, ASN6899, GLY6911, ASP6912, CYS6913 and 4 more
  • 5TBV · Crystal structure of isoform 2 of purine nucleoside phosphorylase complexed with… · TBN A301 · binds SER35, HIS88, TYR90, LEU118, ALA119, GLY120, TYR202, GLU203 and 7 more
  • 6G38 · Crystal structure of haspin in complex with tubercidin · TBN A800 · binds ILE490, GLY491, GLU492, PHE495, VAL498, ALA509, ILE557, PHE605 and 9 more

Residues it binds most

GLY 6, ASP 5, HIS 4, VAL 5, PHE 5, ILE 4, LEU 6, THR 3, ALA 5, ASN 5 (residue and the binding sites it lines).

Found with

  • SO4 · Sulfate ion
  • DMS · Dimethyl sulfoxide
  • ZN · Zinc ion
  • CL · Chloride ion
  • PO4 · Phosphate ion
  • EDO · 1,2-ethanediol
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid
  • MES · 2-(N-morpholino)-ethanesulfonic acid

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