UniProt H2Q5M0
GTPase KRas (H2Q5M0)
GTPase KRas (UniProt H2Q5M0), EC 3.6.5.2: 1 experimental structure on GenesisL1, 3 ligands bound, 2 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- H2Q5M0
- Protein
- GTPase KRas
- EC
- 3.6.5.2
- Experimental structures
- 1
- Predicted models
- 0
- Ligands
- 3
- Pockets
- 2 · 1 record with a druggable one
Structures
1 record of H2Q5M0 in the MolNFT archive: 1 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8WB1 | Crystal Structure of small molecule KN2H covalently bound to K-Ras(G12D) | x-ray diffraction | A | GDP, MG, W3T | 2 (best 0.70) |
Ligands
- GDP · Guanosine-5'-diphosphate · in 1 record
- MG · Magnesium ion · in 1 record
- W3T · 1-[(1~{S},5~{R})-3-[7-(8-ethynyl-7-fluoranyl-3-oxidanyl-naphthalen-1-yl)-8-fluoranyl-2-[[(2~{R},8~{S})-2-fluoranyl-1,2,3,5,6,7-hexahydropyrrolizin-8-yl]methoxy]pyrido[4,3-d]pyrimidin-4-yl]-3,8-diazabicyclo[3.2.1]octan-8-yl]ethanone · in 1 record
Elsewhere
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