UniProt G5EFZ1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase (G5EFZ1)
2,3-bisphosphoglycerate-independent phosphoglycerate mutase (UniProt G5EFZ1), EC 5.4.2.12: 12 experimental structures and 1 predicted model on GenesisL1, 9 ligands bound, 41 pockets. Binding sites, druggability and experiment…
- UniProt
- G5EFZ1
- Protein
- 2,3-bisphosphoglycerate-independent phosphoglycerate mutase
- EC
- 5.4.2.12
- Experimental structures
- 12
- Predicted models
- 1
- Ligands
- 9
- Pockets
- 41 · 6 records with a druggable one
Structures
13 records of G5EFZ1 in the MolNFT archive: 12 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5KGL | 2.45A resolution structure of Apo independent phosphoglycerate mutase from C. elegans (orthorhombic… | x-ray diffraction | A, B | CL, MN, ZN, SO4 | 5 (best 0.69) |
| 5KGL | 2.45A resolution structure of apo independent phosphoglycerate mutase from C. elegans (orthorhombic… | x-ray diffraction | A, B | CL, MN, ZN, SO4 | — |
| 5KGM | 2.95A resolution structure of Apo independent phosphoglycerate mutase from C. elegans (monoclinic… | x-ray diffraction | A, B | CL, MN, ZN | 6 (best 0.81) |
| 5KGM | 2.95A resolution structure of apo independent phosphoglycerate mutase from C. elegans (monoclinic… | x-ray diffraction | A, B | CL, MN, ZN | — |
| 5KGN | 1.95A resolution structure of independent phosphoglycerate mutase from C. elegans in complex with a… | x-ray diffraction | A, B | CL, MG, MN, ZN | 7 (best 0.77) |
| 5KGN | 1.95A resolution structure of independent phosphoglycerate mutase from C. elegans in complex with a… | x-ray diffraction | A, B | NH2, CL, MG, MN, ZN | — |
| 7KNF | 1.80A resolution structure of independent Phosphoglycerate mutase from C. elegans in complex with a… | x-ray diffraction | A, B | ZN, NA | 6 (best 0.72) |
| 7KNF | 1.80A resolution structure of independent phosphoglycerate mutase from C. elegans in complex with a… | x-ray diffraction | A, B | ZN, NA, HOA | — |
| 7KNG | 2.10A resolution structure of independent Phosphoglycerate mutase from C. elegans in complex with a… | x-ray diffraction | A, B | CL, NA, ZN | — |
| 7KNG | 2.10A resolution structure of independent phosphoglycerate mutase from C. elegans in complex with a… | x-ray diffraction | A, B | NH2, CL, NA, ZN | — |
| 7TL7 | 1.90A resolution structure of independent phosphoglycerate mutase from C. elegans in complex with a… | x-ray diffraction | A, B, C, D | ZN, NA | 15 (best 0.83) |
| 7TL7 | 1.90A resolution structure of independent phosphoglycerate mutase from C. elegans in complex with a… | x-ray diffraction | A, B, C, D | ACE, NH2, ZN, NA | — |
| G5EFZ1 | AlphaFold monomer V2.0 prediction for 2,3-bisphosphoglycerate- independent phosphoglycerate mutase… | predicted | A | — | 2 (best 0.53) |
Ligands
Experiment against prediction
- 7TL7 chain C against the predicted model G5EFZ1: TM-score 0.97, RMSD 1.46 Å
- 7TL7 chain C against the predicted model G5EFZ1: TM-score 0.97, RMSD 1.46 Å
- 7TL7 chain D against the predicted model G5EFZ1: TM-score 0.97, RMSD 1.54 Å
- 7TL7 chain D against the predicted model G5EFZ1: TM-score 0.97, RMSD 1.54 Å
- 5KGN chain B against the predicted model G5EFZ1: TM-score 0.96, RMSD 1.68 Å
- 5KGN chain B against the predicted model G5EFZ1: TM-score 0.96, RMSD 1.68 Å
- 7KNF chain B against the predicted model G5EFZ1: TM-score 0.96, RMSD 1.67 Å
- 7KNF chain B against the predicted model G5EFZ1: TM-score 0.96, RMSD 1.67 Å
- 7KNG chain B against the predicted model G5EFZ1: TM-score 0.96, RMSD 1.73 Å
- 7KNG chain B against the predicted model G5EFZ1: TM-score 0.96, RMSD 1.73 Å
Elsewhere
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