UniProt G4FEF4
G4FEF4
G4FEF4 (UniProt G4FEF4): 8 experimental structures and 1 predicted model on GenesisL1, 7 ligands bound. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- G4FEF4
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 7
Structures
9 records of G4FEF4 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6GTA | Alpha-galactosidase mutant D378A from thermotoga maritima in complex with intact cyclohexene-based… | x-ray diffraction | A | SO4, MG, F9W | — |
| 6GVD | Alpha-galactosidase from Thermotoga maritima in complex with cyclohexene-based carbasugar mimic of… | x-ray diffraction | A | SO4, MG, FDK | — |
| 6GVD | Alpha-galactosidase from thermotoga maritima in complex with cyclohexene-based carbasugar mimic of… | x-ray diffraction | A | SO4, MG, FDK | — |
| 6GWF | Alpha-galactosidase mutant D387A from thermotoga maritima in complex with intact cyclohexene-based… | x-ray diffraction | A | SO4, FEQ, MG | — |
| 6GWG | Alpha-galactosidase from Thermotoga maritima in complex with cyclohexene-based carbasugar mimic of… | x-ray diffraction | A | SO4, FEK, MG | — |
| 6GWG | Alpha-galactosidase from thermotoga maritima in complex with cyclohexene-based carbasugar mimic of… | x-ray diffraction | A | SO4, FEK, MG | — |
| 6GX8 | Alpha-galactosidase from Thermotoga maritima in complex with hydrolysed cyclohexene-based… | x-ray diffraction | A | SO4, FH2, MG | — |
| 6GX8 | Alpha-galactosidase from thermotoga maritima in complex with hydrolysed cyclohexene-based… | x-ray diffraction | A | SO4, FH2, MG | — |
| G4FEF4 | AlphaFold monomer V2.0 prediction for alpha-galactosidase (G4FEF4) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 8 records
- SO4 · Sulfate ion · in 8 records
- FDK · (1~{S},2~{S},3~{S},4~{S})-5-(hydroxymethyl)cyclohex-5-ene-1,2,3,4-tetrol · in 2 records
- FEK · (1~{S},2~{S},3~{S})-3-fluoranyl-6-(hydroxymethyl) cyclohex-5-ene-1,2,4-triol · in 2 records
- FH2 · (1~{S},2~{S},3~{S},4~{S})-3-fluoranyl-6-(hydroxymethyl)cyclohex-5-ene-1,2,4-triol · in 2 records
- F9W · (1~{R},2~{S},3~{S},6~{S})-6-[3,5-bis(fluoranyl) phenoxy]-4-(hydroxymethyl)cyclohex-4-ene-1,2,3-triol · in 1 record
- FEQ · (1~{S},2~{S},5~{S},6~{R})-5-(2,4-dinitrophenoxy)-6-fluoranyl-3-(hydroxymethyl)cyclohex-3-ene-1,2-diol · in 1 record
Experiment against prediction
- 6GVD chain A against the predicted model G4FEF4: TM-score 0.98, RMSD 0.61 Å
- 6GVD chain A against the predicted model G4FEF4: TM-score 0.98, RMSD 0.61 Å
- 6GWG chain A against the predicted model G4FEF4: TM-score 0.98, RMSD 0.51 Å
- 6GWG chain A against the predicted model G4FEF4: TM-score 0.98, RMSD 0.51 Å
- 6GTA chain A against the predicted model G4FEF4: TM-score 0.98, RMSD 0.65 Å
- 6GX8 chain A against the predicted model G4FEF4: TM-score 0.98, RMSD 0.57 Å
- 6GX8 chain A against the predicted model G4FEF4: TM-score 0.98, RMSD 0.57 Å
- 6GWF chain A against the predicted model G4FEF4: TM-score 0.98, RMSD 0.56 Å
Elsewhere
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