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UniProt G3V845

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma (G3V845)

1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma (UniProt G3V845), EC 3.1.4.11: 3 experimental structures on GenesisL1, 2 ligands bound, 31 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
G3V845
Protein
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma
EC
3.1.4.11
Experimental structures
3
Predicted models
0
Ligands
2
Pockets
31 · 2 records with a druggable one

Structures

3 records of G3V845 in the MolNFT archive: 3 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6PBCStructural basis for the activation of PLC-gamma isozymes by phosphorylation and cancer-associated…x-ray diffractionACA, NA11 (best 0.76)
6PBCStructural basis for the activation of plc-gamma isozymes by phosphorylation and cancer-associated…x-ray diffractionACA, NA—
7T8TCryoEM structure of PLCg1electron microscopyACA20 (best 0.78)

Ligands

  • CA · Calcium ion · in 3 records
  • NA · Sodium ion · in 2 records

Elsewhere

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