UniProt G3ECR3
CRISPR-associated endoribonuclease Cas2 (G3ECR3)
CRISPR-associated endoribonuclease Cas2 (UniProt G3ECR3), EC 3.1.-.-: 8 experimental structures and 1 predicted model on GenesisL1, 1 ligand bound, 70 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- G3ECR3
- Protein
- CRISPR-associated endoribonuclease Cas2
- EC
- 3.1.-.-
- Experimental structures
- 8
- Predicted models
- 1
- Ligands
- 1
- Pockets
- 70 · 6 records with a druggable one
Structures
9 records of G3ECR3 in the MolNFT archive: 8 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6QXF | Cas1-Cas2-Csn2-DNA complex from the Type II-A CRISPR-Cas system | electron microscopy | K, N, Q, T | — | — |
| 6QXF | CAS1-CAS2-CSN2-DNA complex from the type II-a CRISPR-CAS system | electron microscopy | K, N, Q, T | — | — |
| 6QXT | Cas1-Cas2-Csn2-DNA dimer complex from the Type II-A CRISPR-Cas system | electron microscopy | K, N, Q, T, W, X, k, n, q, t, w, x | — | 13 (best 0.83) |
| 6QXT | CAS1-CAS2-CSN2-DNA dimer complex from the type II-a CRISPR-CAS system | electron microscopy | K, N, Q, T, W, X, k, n, q, t, w, x | — | 13 (best 0.83) |
| 6QY3 | Segment of the Cas1-Cas2-Csn2-DNA filament complex from the Type II-A CRISPR-Cas system | electron microscopy | K, N, Q, T, W, X, k, n, q, t, w, x | — | 14 (best 0.83) |
| 6QY3 | Segment of the CAS1-CAS2-CSN2-DNA filament complex from the type II-a CRISPR-CAS system | electron microscopy | K, N, Q, T, W, X, k, n, q, t, w, x | — | 14 (best 0.83) |
| 8PK1 | Cas1-Cas2 CRISPR integrase bound to prespacer DNA, Streptococcus thermophilus DGCC 7710 CRISPR3… | electron microscopy | A, D | MG | 8 (best 0.74) |
| 8Q2N | Cas1-Cas2 CRISPR integrase bound to prespacer and target DNA, Streptococcus thermophilus DGCC 7710… | electron microscopy | A, D | MG | 8 (best 0.78) |
| G3ECR3 | AlphaFold monomer V2.0 prediction for CRISPR-associated endoribonuclease CAS2 (G3ECR3) | predicted | A | — | — |
Ligands
- MG · Magnesium ion · in 2 records
Experiment against prediction
- 8PK1 chain D against the predicted model G3ECR3: TM-score 0.94, RMSD 1.09 Å
- 8PK1 chain A against the predicted model G3ECR3: TM-score 0.94, RMSD 1.10 Å
- 8Q2N chain D against the predicted model G3ECR3: TM-score 0.93, RMSD 1.13 Å
- 8Q2N chain A against the predicted model G3ECR3: TM-score 0.93, RMSD 1.13 Å
- 6QXT chain n against the predicted model G3ECR3: TM-score 0.80, RMSD 1.43 Å
- 6QXT chain n against the predicted model G3ECR3: TM-score 0.80, RMSD 1.43 Å
- 6QXT chain N against the predicted model G3ECR3: TM-score 0.80, RMSD 1.43 Å
- 6QXT chain N against the predicted model G3ECR3: TM-score 0.80, RMSD 1.43 Å
- 6QXT chain T against the predicted model G3ECR3: TM-score 0.80, RMSD 1.43 Å
- 6QXT chain T against the predicted model G3ECR3: TM-score 0.80, RMSD 1.43 Å
Elsewhere
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