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UniProt F5B5W8

ADP-ribosyltransferase (F5B5W8)

ADP-ribosyltransferase (UniProt F5B5W8): 10 experimental structures on GenesisL1, 5 ligands bound, 46 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
F5B5W8
Protein
ADP-ribosyltransferase
Experimental structures
10
Predicted models
0
Ligands
5
Pockets
46 · 5 records with a druggable one

Structures

10 records of F5B5W8 in the MolNFT archive: 10 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
6X41Crystal structure of inactive enzymatic binary toxin component from clostridium difficilex-ray diffractionA, B——
6X6RCrystal structure of C.difficile ribosyltransferase CDTa in complex with pCl-phenylthioDADMeImmAx-ray diffractionA, B4CT, AR610 (best 0.66)
6X6RCrystal structure of C.DIFFICILE ribosyltransferase cdta in complex with pcl-phenylthiodadmeimmax-ray diffractionA, B4CT, AR6—
6X6VCrystal structure of inactive enzymatic binary toxin component from Clostridium difficile in…x-ray diffractionA, B, C, DNDP16 (best 0.74)
6X6VCrystal structure of inactive enzymatic binary toxin component from clostridium difficile in…x-ray diffractionA, B, C, DNDP—
6X6WCrystal structure of inactive enzymatic binary toxin component from Clostridium difficilex-ray diffractionB—5 (best 0.55)
6X6WCrystal structure of inactive enzymatic binary toxin component from clostridium difficilex-ray diffractionB——
6X6XCrystal structure of enzymatic binary toxin component from Clostridium difficile in complex withx-ray diffractionA, BZN, UTG9 (best 0.65)
6X6XCrystal structure of enzymatic binary toxin component from clostridium difficile in complex withx-ray diffractionA, BZN, UTG—
7VNNComplex structure of Clostridioides difficile enzymatic component (CDTa) and binding component…electron microscopyH—6 (best 0.85)

Ligands

  • 4CT · (3R,4S)-1-[(4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl) methyl]-4-{[(4-chlorophenyl) sulfanyl]methyl}pyrrolidin-3-ol · in 2 records
  • AR6 · [(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-3,4-dihydroxy-oxolan-2-yl]methyl [hydroxy-[[(2R,3S,4R,5S)-3,4,5-trihydroxyoxolan-2-yl]methoxy]phosphoryl] hydrogen phosphate · in 2 records
  • NDP · Nadph dihydro-nicotinamide-adenine-dinucleotide phosphate · in 2 records
  • UTG · N-(2-chlorophenyl)-N'-[(furan-2-yl)methyl]thiourea · in 2 records
  • ZN · Zinc ion · in 2 records

Elsewhere

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