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UniProt F1RM59

Sodium/potassium-transporting ATPase subunit alpha (F1RM59)

Sodium/potassium-transporting ATPase subunit alpha (UniProt F1RM59): 5 experimental structures on GenesisL1, 9 ligands bound, 78 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt
F1RM59
Protein
Sodium/potassium-transporting ATPase subunit alpha
Experimental structures
5
Predicted models
0
Ligands
9
Pockets
78 · 5 records with a druggable one

Structures

5 records of F1RM59 in the MolNFT archive: 5 experimental, 0 predicted.

EntryTitleMethodChainsLigandsPockets
8IJVCryo-EM structure of the gastric proton pump with bound DQ-02electron microscopyAPCW, MG, PWI, CLR16 (best 0.76)
8IJWCryo-EM structure of the gastric proton pump with bound DQ-06electron microscopyAPCW, MG, PXR, CLR15 (best 0.77)
8IJXCryo-EM structure of the gastric proton pump with bound DQ-18electron microscopyAPCW, MG, PZ0, CLR18 (best 0.77)
8JMNCryo-EM structure of the gastric proton pump with bound DQ-21electron microscopyAPCW, MG, UOU, CLR15 (best 0.77)
8WA5Cryo-EM structure of the gastric proton pump Y799W/E936Q mutant in K+-occluded (K+)E2-AlF stateelectron microscopyAK, ALF, MG, CLR, PCW14 (best 0.75)

Ligands

  • CLR · Cholesterol · in 5 records
  • MG · Magnesium ion · in 5 records
  • PCW · 1,2-dioleoyl-sn-glycero-3-phosphocholine · in 5 records
  • ALF · Tetrafluoroaluminate ion · in 1 record
  • K · Potassium ion · in 1 record
  • PWI · 4-[[5-chloranyl-2-(4-chlorophenyl)phenyl]methoxy]-N-methyl-but-2-yn-1-amine · in 1 record
  • PXR · N-methyl-1-[4-[(2-phenylmethoxycyclohexa-1,3-dien-1-yl)methoxy]cyclohexa-1,3-dien-1-yl]methanamine · in 1 record
  • PZ0 · 1-[4-[(5-chloranyl-2-phenylmethoxy-phenyl)methoxy]phenyl]-N-methyl-methanamine · in 1 record
  • UOU · 1-[4-[[2-[(4-chlorophenyl)methoxy]phenyl]methoxy]phenyl]-N-methyl-methanamine · in 1 record

Elsewhere

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