UniProt E9Q401
Ryanodine receptor 2 (E9Q401)
Ryanodine receptor 2 (UniProt E9Q401): 42 experimental structures on GenesisL1, 7 ligands bound, 136 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- E9Q401
- Protein
- Ryanodine receptor 2
- Experimental structures
- 42
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 136 · 8 records with a druggable one
Structures
42 records of E9Q401 in the MolNFT archive: 42 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 2MC2 | X-ray crystallography-solution NMR hybrid structure of mouse RyR2 domain A | solution nmr | A | — | — |
| 2MC2 | X-ray crystallography-solution NMR hybrid structure of mouse RYR2 domain a | solution nmr | A | — | — |
| 4ETV | Crystal structure of mouse ryanodine receptor 2 (2699-2904) | x-ray diffraction | A, B | — | — |
| 4ETV | Crystal structure of mouse ryanodine receptor 2 (2699-2904) | x-ray diffraction | A, B | — | — |
| 4KEI | Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant P164S | x-ray diffraction | A | — | — |
| 4KEI | Crystal structure of mouse ryanodine receptor 2 (1-217) disease mutant P164S | x-ray diffraction | A | — | — |
| 4KEJ | Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant R169Q | x-ray diffraction | A | — | — |
| 4KEJ | Crystal structure of mouse ryanodine receptor 2 (1-217) disease mutant R169Q | x-ray diffraction | A | — | — |
| 4KEK | Crystal structure of mouse Ryanodine Receptor 2 (1-217) disease mutant R176Q | x-ray diffraction | A | — | — |
| 4KEK | Crystal structure of mouse ryanodine receptor 2 (1-217) disease mutant R176Q | x-ray diffraction | A | — | — |
| 4L4H | Crystal structure of mouse Ryanodine Receptor isoform 2 (RyR2) 1-547 | x-ray diffraction | A | — | — |
| 4L4H | Crystal structure of mouse ryanodine receptor isoform 2 (RYR2) 1-547 | x-ray diffraction | A | — | — |
| 4L4I | Crystal structure of mouse Ryanodine Receptor isoform 2 (RyR2) 1-547 disease mutant R420Q | x-ray diffraction | A | — | — |
| 4L4I | Crystal structure of mouse ryanodine receptor isoform 2 (RYR2) 1-547 disease mutant R420Q | x-ray diffraction | A | — | — |
| 4P9I | Crystal Structure of mouse Ryanodine Receptor 2 SPRY2 Domain (1080-1253) | x-ray diffraction | A | — | — |
| 4P9I | Crystal structure of mouse ryanodine receptor 2 SPRY2 domain (1080- 1253) | x-ray diffraction | A | — | — |
| 4P9L | Crystal Structure of mouse Ryanodine Receptor 2 SPRY2 Domain (1080-1253) disease mutant A1107M | x-ray diffraction | A | — | — |
| 4P9L | Crystal structure of mouse ryanodine receptor 2 SPRY2 domain (1080- 1253) disease mutant A1107M | x-ray diffraction | A | — | — |
| 5C33 | Crystal Structure of Mouse Ryanodine Receptor 2 SPRY1 Domain | x-ray diffraction | A, B | CL | 6 (best 0.67) |
| 5C33 | Crystal structure of mouse ryanodine receptor 2 SPRY1 domain | x-ray diffraction | A, B | — | — |
| 5VSN | Crystal structure of mouse ryanodine receptor 2 SPRY2 domain (1080-1253) disease mutant P1124L | x-ray diffraction | A | K | — |
| 5VSN | Crystal structure of mouse ryanodine receptor 2 SPRY2 domain (1080- 1253) disease mutant P1124L | x-ray diffraction | A | K | — |
| 6J6L | Crystal structure of mouse Ryanodine Receptor 2 SPRY1 Domain (650-844) disease mutant I784F | x-ray diffraction | A, B | — | 9 (best 0.57) |
| 6J6L | Crystal structure of mouse ryanodine receptor 2 SPRY1 domain (650-844) disease mutant I784F | x-ray diffraction | A, B | — | — |
| 6MM5 | Catalytic subunit of camp-dependent protein kinase a in complex with RYR2 peptide (2799-2810) | x-ray diffraction | C | ANP | — |
| 6MM6 | Catalytic subunit of cAMP-dependent protein kinase A in complex with RyR2 phosphorylation domain… | x-ray diffraction | F, D | CL | — |
| 6MM6 | Catalytic subunit of camp-dependent protein kinase a in complex with RYR2 phosphorylation domain… | x-ray diffraction | F, D | CL | — |
| 6MM7 | Catalytic subunit of camp-dependent protein kinase a in complex with RYR2 K2879A, S2813D… | x-ray diffraction | C, E | ANP, CL | — |
| 6MM8 | Catalytic subunit of cAMP-dependent protein kinase A in complex with RyR2 K2879A, S2813D… | x-ray diffraction | D | ANP, CL | — |
| 6MM8 | Catalytic subunit of camp-dependent protein kinase a in complex with RYR2 K2879A, S2813D… | x-ray diffraction | D | ANP, CL | — |
| 6WOU | Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 mutant R176Q in complex with… | electron microscopy | A, B, C, D | ZN | — |
| 6WOV | Cryo-EM structure of recombinant mouse Ryanodine Receptor type 2 wild type in complex with FKBP12.6 | electron microscopy | A, B, C, D | ZN | 20 (best 0.89) |
| 6Y4O | Calmodulin bound to cardiac ryanodine receptor (RyR2) calmodulin binding domain | x-ray diffraction | B | — | 1 (best 0.49) |
| 6Y4O | Calmodulin bound to cardiac ryanodine receptor (RYR2) calmodulin binding domain | x-ray diffraction | B | — | — |
| 6Y4P | Calmodulin N53I variant bound to cardiac ryanodine receptor (RYR2) calmodulin binding domain | x-ray diffraction | B | — | — |
| 7VMN | Structure of recombinant RyR2 (EGTA dataset, class 2, closed state) | electron microscopy | A, B, C, D | ZN | — |
| 7VMQ | Structure of recombinant RyR2 (Ca2+ dataset, class 3, open state) | electron microscopy | A, B, C, D | ZN, CA | — |
| 7VMR | Structure of recombinant RyR2 mutant K4593A (EGTA dataset) | electron microscopy | A, B, C, D | ZN | 20 (best 0.85) |
| 7VMS | Structure of recombinant RyR2 mutant K4593A (Ca2+ dataset) | electron microscopy | A, B, C, D | ZN, CA | 20 (best 0.87) |
| 8DTY | Recombinant mouse RyR2 triple phosphomimetic mutant S2807D/S2813D/S2030D in complex with FKBP12.6… | electron microscopy | A, B, C, D | ZN | 20 (best 0.88) |
| 8DTZ | Recombinant mouse RyR2 triple phosphonull mutant S2807A/S2813A/S2030A in complex with FKBP12.6 and… | electron microscopy | A, B, C, D | ZN | 20 (best 0.89) |
| 8RRS | Structure of mouse RyR2 solubilised in detergent in open state in complex with Ca2+, ATP, caffeine… | electron microscopy | A, C, E, F | ATP, CFF, ZN, CA | 20 (best 0.83) |
Ligands
Elsewhere
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