UniProt E9PZQ0

Ryanodine receptor 1 (E9PZQ0)

Ryanodine receptor 1 (UniProt E9PZQ0): 3 experimental structures on GenesisL1, 5 ligands bound, 60 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.

UniProt: E9PZQ0
Protein: Ryanodine receptor 1
Experimental structures: 3
Predicted models: 0
Ligands: 5
Pockets: 60 · 3 records with a druggable one

Structures

3 records of E9PZQ0 in the MolNFT archive: 3 experimental, 0 predicted.

Entry	Title	Method	Chains	Ligands	Pockets
8VJJ	Structure of mouse RyR1 (EGTA-only dataset)	electron microscopy	A, D, B, C	ZN, PCW	20 (best 0.84)
8VJK	Structure of mouse RyR1 (high-Ca2+/CFF/ATP dataset)	electron microscopy	A, B, C, D	ZN, CFF, ATP, CA, PCW	20 (best 0.84)
8VK3	Structure of mouse RyR1 in complex with S100A1 (EGTA-only dataset)	electron microscopy	A, D, B, C	ZN, PCW	20 (best 0.85)

Ligands

PCW · 1,2-dioleoyl-sn-glycero-3-phosphocholine · in 3 records
ZN · Zinc ion · in 3 records
ATP · Adenosine-5'-triphosphate · in 1 record
CA · Calcium ion · in 1 record
CFF · Caffeine · in 1 record

Elsewhere

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