UniProt E8RUP5
AtxE2 (E8RUP5)
AtxE2 (UniProt E8RUP5), EC 3.4.21.-: 4 experimental structures and 1 predicted model on GenesisL1, 26 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- E8RUP5
- Protein
- AtxE2
- EC
- 3.4.21.-
- Experimental structures
- 4
- Predicted models
- 1
- Pockets
- 26 · 2 records with a druggable one
Structures
5 records of E8RUP5 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5TXC | AtxE2 Isopeptidase - APO | x-ray diffraction | A, B | — | 12 (best 0.75) |
| 5TXC | ATXE2 isopeptidase - apo | x-ray diffraction | A, B | — | — |
| 5TXE | AtxE2 Isopeptidase - S527A Variant with Astexin3-dC4 Bound | x-ray diffraction | A, B | — | 14 (best 0.82) |
| 5TXE | ATXE2 isopeptidase - S527A variant with ASTEXIN3-DC4 bound | x-ray diffraction | A, B | — | — |
| E8RUP5 | AlphaFold monomer V2.0 prediction for lasso peptide isopeptidase ATXE2 (E8RUP5) | predicted | A | — | — |
Experiment against prediction
- 5TXE chain B against the predicted model E8RUP5: TM-score 1.00, RMSD 0.19 Å
- 5TXE chain B against the predicted model E8RUP5: TM-score 1.00, RMSD 0.19 Å
- 5TXE chain A against the predicted model E8RUP5: TM-score 1.00, RMSD 0.40 Å
- 5TXE chain A against the predicted model E8RUP5: TM-score 1.00, RMSD 0.40 Å
- 5TXC chain A against the predicted model E8RUP5: TM-score 1.00, RMSD 0.49 Å
- 5TXC chain A against the predicted model E8RUP5: TM-score 1.00, RMSD 0.49 Å
- 5TXC chain B against the predicted model E8RUP5: TM-score 0.99, RMSD 0.66 Å
- 5TXC chain B against the predicted model E8RUP5: TM-score 0.99, RMSD 0.66 Å
Elsewhere
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