UniProt E6Y8U5
Proton-coupled folate transporter (E6Y8U5)
Proton-coupled folate transporter (UniProt E6Y8U5): 4 experimental structures on GenesisL1, 1 ligand bound, 14 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- E6Y8U5
- Protein
- Proton-coupled folate transporter
- Experimental structures
- 4
- Predicted models
- 0
- Ligands
- 1
- Pockets
- 14 · 4 records with a druggable one
Structures
4 records of E6Y8U5 in the MolNFT archive: 4 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 7BC6 | Cryo-EM structure of the outward open proton coupled folate transporter at pH 7.5 | electron microscopy | A | — | 3 (best 0.85) |
| 7BC6 | Cryo-EM structure of the outward open proton coupled folate transporter at pH 7.5 | electron microscopy | A | — | 3 (best 0.85) |
| 7BC7 | Cryo-EM structure of the proton coupled folate transporter at pH 6.0 bound to pemetrexed | electron microscopy | A | LYA | 4 (best 0.84) |
| 7BC7 | Cryo-EM structure of the proton coupled folate transporter at pH 6.0 bound to pemetrexed | electron microscopy | A | LYA | 4 (best 0.84) |
Ligands
- LYA · 2-{4-[2-(2-amino-4-oxo-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-5-yl)-ethyl]-benzoylamino}-pentanedioic acid · in 2 records
Elsewhere
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