UniProt E3ULB4
Keratinase KP2 (E3ULB4)
Keratinase KP2 (UniProt E3ULB4), EC 3.4.24.-: 5 experimental structures on GenesisL1, 7 ligands bound, 19 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- E3ULB4
- Protein
- Keratinase KP2
- EC
- 3.4.24.-
- Experimental structures
- 5
- Predicted models
- 0
- Ligands
- 7
- Pockets
- 19 · 4 records with a druggable one
Structures
5 records of E3ULB4 in the MolNFT archive: 5 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6FZX | LasB, hydroxymate Inhibitor Complex | x-ray diffraction | A | EEK, ZN, CA, SO4 | 2 (best 0.51) |
| 6FZX | Lasb, hydroxymate inhibitor complex | x-ray diffraction | A | EEK, ZN, CA, SO4 | — |
| 7AJR | Virtual screening approach leading to the identification of a novel and tractable series of… | x-ray diffraction | AAA | RJB, ZN, SO4 | 3 (best 0.55) |
| 7QH1 | Discovery and development of a novel inhaled antivirulence therapy for the treatment of Pseudomonas… | x-ray diffraction | A, B, C, D | ZN, CI8, CA | 13 (best 0.75) |
| 7Z68 | Pseudomonas aeruginosa Elastase in complex with a Thiol based inhibitor (R-and S-configured) | x-ray diffraction | A | CA, ZN, IEV | 1 (best 0.53) |
Ligands
- ZN · Zinc ion · in 5 records
- CA · Calcium ion · in 4 records
- SO4 · Sulfate ion · in 3 records
- EEK · ~{N}-(3,4-dichlorophenyl)-~{N}'-oxidanyl-propanediamide · in 2 records
- CI8 · 2-[2-[[5-[3-[bis(2-hydroxyethyl)-methyl-$l^{4}-azanyl]propoxy]-6-methoxy-1,3-benzothiazol-2-yl]methylcarbamoyl]-5,6-bis(fluoranyl)-1,3-dihydroinden-2-yl]ethanoic acid · in 1 record
- IEV · (2~{R})-~{N}-[4-[(2~{S},3~{R},4~{S},5~{R},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]sulfanylphenyl]-3-phenyl-2-sulfanyl-propanamide · in 1 record
- RJB · 2-[2-(1,3-benzothiazol-2-ylmethylcarbamoyl)-1,3-dihydroinden-2-yl]ethanoic acid · in 1 record
Elsewhere
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