UniProt D6WMX4
Serine/threonine-protein kinase PINK1, mitochondrial-like Protein (D6WMX4)
Serine/threonine-protein kinase PINK1, mitochondrial-like Protein (UniProt D6WMX4): 9 experimental structures on GenesisL1, 6 ligands bound, 18 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- D6WMX4
- Protein
- Serine/threonine-protein kinase PINK1, mitochondrial-like Protein
- Experimental structures
- 9
- Predicted models
- 0
- Ligands
- 6
- Pockets
- 18 · 4 records with a druggable one
Structures
9 records of D6WMX4 in the MolNFT archive: 9 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5OAT | PINK1 structure | x-ray diffraction | A, B, C, D, E, F | MG | — |
| 5OAT | PINK1 structure | x-ray diffraction | A, B, C, D, E, F | MG | — |
| 5YJ9 | Crystal structure of Tribolium castaneum PINK1 kinase domain in complex with AMP-PNP | x-ray diffraction | D | ANP, MG | 3 (best 0.60) |
| 5YJ9 | Crystal structure of tribolium castaneum PINK1 kinase domain in complex with AMP-pnp | x-ray diffraction | D | ANP, MG | — |
| 7MP8 | Crystal structure of the cytosolic domain of Tribolium castaneum PINK1 in the non-phosphorylated… | x-ray diffraction | A | SO4 | 5 (best 0.63) |
| 7MP8 | Crystal structure of the cytosolic domain of tribolium castaneum PINK1 in the non-phosphorylated… | x-ray diffraction | A | SO4 | — |
| 7MP9 | Crystal structure of the cytosolic domain of tribolium castaneum PINK1 phosphorylated at SER205 in… | x-ray diffraction | A | MG, SO4, AN2 | — |
| 8UCT | Crystal structure of TcPINK1 in complex with PRT | x-ray diffraction | A | SO4, 3YT | 5 (best 0.60) |
| 8UDC | Crystal structure of TcPINK1 in complex with CYC116 | x-ray diffraction | A | SO4, WCK | 5 (best 0.66) |
Ligands
- MG · Magnesium ion · in 5 records
- SO4 · Sulfate ion · in 5 records
- ANP · Phosphoaminophosphonic acid-adenylate ester · in 2 records
- 3YT · 2-{[(1R,2S)-2-aminocyclohexyl]amino}-4-{[3-(2H-1,2,3-triazol-2-yl)phenyl]amino}pyrimidine-5-carboxamide · in 1 record
- AN2 · Amp phosphoramidate · in 1 record
- WCK · (4P)-4-(2-amino-4-methyl-1,3-thiazol-5-yl)-N-[4-(morpholin-4-yl)phenyl]pyrimidin-2-amine · in 1 record
Elsewhere
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