UniProt D5FKJ3
2-ketoarginine methyltransferase (D5FKJ3)
2-ketoarginine methyltransferase (UniProt D5FKJ3), EC 2.1.1.243: 4 experimental structures and 1 predicted model on GenesisL1, 4 ligands bound, 27 pockets. Binding sites, druggability and experiment against prediction (TM-score)…
- UniProt
- D5FKJ3
- Protein
- 2-ketoarginine methyltransferase
- EC
- 2.1.1.243
- Experimental structures
- 4
- Predicted models
- 1
- Ligands
- 4
- Pockets
- 27 · 5 records with a druggable one
Structures
5 records of D5FKJ3 in the MolNFT archive: 4 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8R4Z | Crystal structure of alpha keto acid C-methyl-transferases MrsA native-form | x-ray diffraction | A, B | MG | 6 (best 0.79) |
| 8RVC | Crystal structure of alpha keto acid C-methyl-transferases MrsA bound to ketoarginine | x-ray diffraction | A, B | NWG, MG, NA | 6 (best 0.76) |
| 8RVS | Crystal structure of alpha keto acid C-methyl-transferases MrsA bound to SAM | x-ray diffraction | A, B | MG, SAM, NA | 6 (best 0.72) |
| 8RWM | Crystal structure of selenomethionine derivatized alpha keto acid C-methyl-transferases MrsA | x-ray diffraction | A, B | MG, NA | 6 (best 0.73) |
| D5FKJ3 | AlphaFold monomer V2.0 prediction for 2-ketoarginine methyltransferase (D5FKJ3) | predicted | A | — | 3 (best 0.75) |
Ligands
Experiment against prediction
- 8R4Z chain B against the predicted model D5FKJ3: TM-score 0.98, RMSD 1.15 Å
- 8R4Z chain A against the predicted model D5FKJ3: TM-score 0.97, RMSD 1.18 Å
- 8RVC chain B against the predicted model D5FKJ3: TM-score 0.97, RMSD 1.15 Å
- 8RVS chain A against the predicted model D5FKJ3: TM-score 0.97, RMSD 1.21 Å
- 8RWM chain B against the predicted model D5FKJ3: TM-score 0.97, RMSD 1.22 Å
- 8RVC chain A against the predicted model D5FKJ3: TM-score 0.97, RMSD 1.18 Å
- 8RWM chain A against the predicted model D5FKJ3: TM-score 0.97, RMSD 1.26 Å
- 8RVS chain B against the predicted model D5FKJ3: TM-score 0.97, RMSD 1.26 Å
Elsewhere
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