UniProt D2Z025
N(omega)-hydroxy-L-arginine amidinohydrolase (D2Z025)
N(omega)-hydroxy-L-arginine amidinohydrolase (UniProt D2Z025), EC 3.5.3.25: 16 experimental structures and 1 predicted model on GenesisL1, 6 ligands bound, 40 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- D2Z025
- Protein
- N(omega)-hydroxy-L-arginine amidinohydrolase
- EC
- 3.5.3.25
- Experimental structures
- 16
- Predicted models
- 1
- Ligands
- 6
- Pockets
- 40 · 10 records with a druggable one
Structures
17 records of D2Z025 in the MolNFT archive: 16 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 6LUG | Crystal structure of N(omega)-hydroxy-L-arginine hydrolase | x-ray diffraction | A, B | MN | 4 (best 0.77) |
| 6LUG | Crystal structure of N(OMEGA)-hydroxy-L-arginine hydrolase | x-ray diffraction | A, B | MN | — |
| 6LUH | High resolution structure of N(omega)-hydroxy-L-arginine hydrolase | x-ray diffraction | A, B | MN, MG | 4 (best 0.77) |
| 6LUH | High resolution structure of N(OMEGA)-hydroxy-L-arginine hydrolase | x-ray diffraction | A, B | MN, MG | — |
| 7EUK | Crystal structure of N(omega)-hydroxy-L-arginine hydrolase in complex with L-Orn | x-ray diffraction | A, B | MN, MG, ORN | 5 (best 0.73) |
| 7EUK | Crystal structure of N(OMEGA)-hydroxy-L-arginine hydrolase in complex with L-orn | x-ray diffraction | A, B | MN, MG | — |
| 7EUL | Crystal structure of C86H-H196S mutant of N(omega)-hydroxy-L-arginine hydrolase | x-ray diffraction | A | MN, MG | 2 (best 0.50) |
| 7EUL | Crystal structure of C86H-H196S mutant of N(OMEGA)-hydroxy-L-arginine hydrolase | x-ray diffraction | A | MN | — |
| 7EUN | Crystal structure of N(omega)-hydroxy-L-arginine hydrolase in complex with ABH | x-ray diffraction | A, B | MN, MG, ABH | 4 (best 0.80) |
| 7EUN | Crystal structure of N(OMEGA)-hydroxy-L-arginine hydrolase in complex with abh | x-ray diffraction | A, B | MN, MG | — |
| 7EUQ | Crystal structure of C86H-Y124N-G126H-H196S mutant of N(OMEGA)- hydroxy-L-arginine hydrolase | x-ray diffraction | A, B | MN, MG | — |
| 9IXC | Crystal structure of Manganese-rebound N(omega)-hydroxy-L-arginine hydrolase with oxidized Cys86 | x-ray diffraction | A, B | MN, MG | 5 (best 0.75) |
| 9IXD | Crystal structure of Copper-bound N(omega)-hydroxy-L-arginine hydrolase with oxidized Cys86 | x-ray diffraction | A, B | MN, MG, CU, CU1 | 4 (best 0.81) |
| 9IXE | Crystal structure of Copper-bound N(omega)-hydroxy-L-arginine hydrolase without oxidized Cys86 | x-ray diffraction | A, B | MN, MG, CU1 | 4 (best 0.81) |
| 9IXF | Crystal structure of Manganese-free N(omega)-hydroxy-L-arginine hydrolase with oxidized Cys86. | x-ray diffraction | A, B | MN, MG | 4 (best 0.80) |
| 9IXG | Crystal structure of Manganese-free N(omega)-hydroxy-L-arginine hydrolase without oxidized Cys86 | x-ray diffraction | A, B | MN, MG | 4 (best 0.73) |
| D2Z025 | AlphaFold monomer V2.0 prediction for N(OMEGA)-hydroxy-L-arginine amidinohydrolase (D2Z025) | predicted | A | — | — |
Ligands
Experiment against prediction
- 7EUQ chain A against the predicted model D2Z025: TM-score 0.99, RMSD 0.78 Å
- 6LUG chain B against the predicted model D2Z025: TM-score 0.99, RMSD 0.84 Å
- 6LUG chain B against the predicted model D2Z025: TM-score 0.99, RMSD 0.84 Å
- 7EUN chain B against the predicted model D2Z025: TM-score 0.98, RMSD 0.84 Å
- 7EUN chain B against the predicted model D2Z025: TM-score 0.98, RMSD 0.84 Å
- 7EUK chain B against the predicted model D2Z025: TM-score 0.99, RMSD 0.84 Å
- 7EUK chain B against the predicted model D2Z025: TM-score 0.98, RMSD 0.84 Å
- 9IXC chain B against the predicted model D2Z025: TM-score 0.99, RMSD 0.84 Å
- 9IXD chain B against the predicted model D2Z025: TM-score 0.98, RMSD 0.84 Å
- 7EUQ chain B against the predicted model D2Z025: TM-score 0.99, RMSD 0.79 Å
Elsewhere
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.