UniProt D1A7C3
Formylglycine-generating enzyme (D1A7C3)
Formylglycine-generating enzyme (UniProt D1A7C3), EC 1.8.3.7, 2.7.11.1: 21 experimental structures and 1 predicted model on GenesisL1, 10 ligands bound, 27 pockets. Binding sites, druggability and experiment against prediction…
- UniProt
- D1A7C3
- Protein
- Formylglycine-generating enzyme
- EC
- 1.8.3.7, 2.7.11.1
- Experimental structures
- 21
- Predicted models
- 1
- Ligands
- 10
- Pockets
- 27 · 2 records with a druggable one
Structures
22 records of D1A7C3 in the MolNFT archive: 21 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5NXL | Formylglycine generating enzyme from T. curvata in complex with Ag(I) | x-ray diffraction | A | AG, CA | 1 (best 0.57) |
| 5NXL | Formylglycine generating enzyme from T. curvata in complex with AG(I) | x-ray diffraction | A | AG, CA | — |
| 5NYY | Formylglycine generating enzyme from T. curvata in complex with Cd(II) | x-ray diffraction | A | CD, CA | 2 (best 0.58) |
| 5NYY | Formylglycine generating enzyme from T. curvata in complex with CD(II) | x-ray diffraction | A | CD, CA | — |
| 6S07 | Structure of formylglycine-generating enzyme at 1.04 A in complex with copper and substrate reveals… | x-ray diffraction | A | CU1, CA, CL | 3 (best 0.42) |
| 6S07 | Structure of formylglycine-generating enzyme at 1.04 a in complex with copper and substrate reveals… | x-ray diffraction | A | BE2, CU1, CA, CL | — |
| 6XTL | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | AG, CA, CL, SOA | — |
| 6XTL | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | AG, CA, CL, SOA | — |
| 6XTM | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | OXY, CA, CL, AG, SOA | 4 (best 0.43) |
| 6XTM | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | OXY, CA, CL, AG, SOA | — |
| 6XTN | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | AG, CA, CL, NO, SOA | 3 (best 0.44) |
| 6XTN | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | AG, CA, CL, NO, SOA | — |
| 6XTO | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | CU1, CA, NO, SOA | 3 (best 0.41) |
| 6XTO | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | CU1, CA, NO, SOA | — |
| 6XTP | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | CU1, CA, OXY, SOA | — |
| 6XTQ | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | CU1, CA, OXY, CL, MG, SOA | 4 (best 0.44) |
| 6XTQ | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | CU1, CA, OXY, CL, MG, SOA | — |
| 6XTR | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | CU1, CA, CL, OXY, SOA | 3 (best 0.41) |
| 6XTR | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | CU1, CA, CL, OXY, SOA | — |
| 6XTS | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | CU1, CA, CL, OXY, SOA | 4 (best 0.42) |
| 6XTS | Crystal structure reveals non-coordinative binding of O2 to the copper center of the… | x-ray diffraction | A | CU1, CA, CL, OXY, SOA | — |
| D1A7C3 | AlphaFold monomer V2.0 prediction for formylglycine-generating enzyme (D1A7C3) | predicted | A | — | — |
Ligands
- CA · Calcium ion · in 21 records
- SOA · Isatoic anhydride · in 15 records
- CL · Chloride ion · in 14 records
- CU1 · Copper (I) ion · in 11 records
- OXY · Oxygen molecule · in 9 records
- AG · Silver ion · in 8 records
- NO · Nitric oxide · in 4 records
- CD · Cadmium ion · in 2 records
- MG · Magnesium ion · in 2 records
- BE2 · 2-aminobenzoic acid · in 1 record
Experiment against prediction
- 6XTP chain A against the predicted model D1A7C3: TM-score 1.00, RMSD 0.45 Å
- 6XTQ chain A against the predicted model D1A7C3: TM-score 0.99, RMSD 0.57 Å
- 6XTQ chain A against the predicted model D1A7C3: TM-score 0.99, RMSD 0.57 Å
- 6XTO chain A against the predicted model D1A7C3: TM-score 0.99, RMSD 0.43 Å
- 6XTO chain A against the predicted model D1A7C3: TM-score 0.99, RMSD 0.43 Å
- 6XTL chain A against the predicted model D1A7C3: TM-score 0.99, RMSD 0.45 Å
- 6XTL chain A against the predicted model D1A7C3: TM-score 0.99, RMSD 0.45 Å
- 6XTS chain A against the predicted model D1A7C3: TM-score 0.99, RMSD 0.45 Å
- 6XTS chain A against the predicted model D1A7C3: TM-score 0.99, RMSD 0.45 Å
- 6XTR chain A against the predicted model D1A7C3: TM-score 0.99, RMSD 0.45 Å
Elsewhere
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