UniProt C7DZL4
NADH-ubiquinone oxidoreductase chain 5 (C7DZL4)
NADH-ubiquinone oxidoreductase chain 5 (UniProt C7DZL4), EC 7.1.1.2: 3 experimental structures on GenesisL1, 4 ligands bound, 18 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- C7DZL4
- Protein
- NADH-ubiquinone oxidoreductase chain 5
- EC
- 7.1.1.2
- Experimental structures
- 3
- Predicted models
- 0
- Ligands
- 4
- Pockets
- 18 · 3 records with a druggable one
Structures
3 records of C7DZL4 in the MolNFT archive: 3 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 8B9Z | Drosophila melanogaster complex I in the Active state (Dm1) | electron microscopy | L | 3PE, EHZ, CDL, PC1 | 6 (best 0.85) |
| 8ESW | Structure of mitochondrial complex I from Drosophila melanogaster, Flexible-class 1 | electron microscopy | 5 | PC1, 3PE, CDL | 7 (best 0.84) |
| 8ESZ | Structure of mitochondrial complex I from Drosophila melanogaster, Helix-locked state | electron microscopy | 5 | PC1, 3PE, CDL | 5 (best 0.83) |
Ligands
- 3PE · 1,2-diacyl-sn-glycero-3-phosphoethanolamine · in 3 records
- CDL · Cardiolipin · in 3 records
- PC1 · 1,2-diacyl-sn-glycero-3-phosphocholine · in 3 records
- EHZ · ~{S}-[2-[3-[[(2~{R})-3,3-dimethyl-2-oxidanyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3~{S})-3-oxidanyltetradecanethioate · in 1 record
Elsewhere
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