UniProt C6KTA4
Pyruvate kinase (C6KTA4)
Pyruvate kinase (UniProt C6KTA4), EC 2.7.1.40: 12 experimental structures on GenesisL1, 5 ligands bound, 70 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- C6KTA4
- Protein
- Pyruvate kinase
- EC
- 2.7.1.40
- Experimental structures
- 12
- Predicted models
- 0
- Ligands
- 5
- Pockets
- 70 · 8 records with a druggable one
Structures
12 records of C6KTA4 in the MolNFT archive: 12 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3KHD | Crystal Structure of PFF1300w. | x-ray diffraction | A, B, C, D | — | — |
| 3KHD | Crystal structure of PFF1300W. | x-ray diffraction | A, B, C, D | — | — |
| 6KSH | Crystal structure of pyruvate kinase (PYK) from Plasmodium falciparum in complex with oxalate and… | x-ray diffraction | A, B, C, D | MG, ATP, K, OXL | 20 (best 0.85) |
| 6KSH | Crystal structure of pyruvate kinase (pyk) from plasmodium falciparum in complex with oxalate and… | x-ray diffraction | A, B, C, D | MG, ATP, K, OXL | — |
| 7Z4M | Plasmodium falciparum pyruvate kinase complexed with Mg2+ and K+ | x-ray diffraction | A | MG, K | 9 (best 0.66) |
| 7Z4M | Plasmodium falciparum pyruvate kinase complexed with MG2+ and K+ | x-ray diffraction | A | MG, K | 9 (best 0.66) |
| 7Z4N | Plasmodium falciparum pyruvate kinase complexed with pyruvate | x-ray diffraction | A | MG, K, PYR | 5 (best 0.73) |
| 7Z4N | Plasmodium falciparum pyruvate kinase complexed with pyruvate | x-ray diffraction | A | MG, K, PYR | 5 (best 0.73) |
| 7Z4Q | Plasmodium falciparum pyruvate kinase mutant - C49A | x-ray diffraction | A | MG | 8 (best 0.63) |
| 7Z4Q | Plasmodium falciparum pyruvate kinase mutant - C49A | — | — | — | |
| 7Z4R | Plasmodium falciparum pyruvate kinase mutant - C343A | x-ray diffraction | A | MG, K | 7 (best 0.67) |
| 7Z4R | Plasmodium falciparum pyruvate kinase mutant - C343A | x-ray diffraction | A | MG, K | 7 (best 0.67) |
Ligands
Elsewhere
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