UniProt B7MFL0
DNA-directed RNA polymerase subunit omega (B7MFL0)
DNA-directed RNA polymerase subunit omega (UniProt B7MFL0), EC 2.7.7.6: 19 experimental structures and 1 predicted model on GenesisL1, 4 pockets. Binding sites, druggability and experiment against prediction (TM-score) in GL1X.
- UniProt
- B7MFL0
- Protein
- DNA-directed RNA polymerase subunit omega
- EC
- 2.7.7.6
- Experimental structures
- 19
- Predicted models
- 1
- Pockets
- 4 · 3 records with a druggable one
Structures
20 records of B7MFL0 in the MolNFT archive: 19 experimental, 1 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 5UI8 | structure of sigmaN-holoenzyme | x-ray diffraction | K | — | 1 (best 0.74) |
| 5UI8 | Structure of sigman-holoenzyme | x-ray diffraction | K | — | — |
| 6AWB | Structure of 30S ribosomal subunit and RNA polymerase complex in non-rotated state | electron microscopy | 05 | — | — |
| 6B6H | The cryo-EM structure of a bacterial class I transcription activation complex | electron microscopy | E | — | 1 (best 0.72) |
| 6B6H | The cryo-EM structure of a bacterial class I transcription activation complex | electron microscopy | E | — | — |
| 6PB4 | The E. COLI class-II cap-dependent transcription activation complex with de novo RNA transcript at… | electron microscopy | E | — | — |
| 6PB5 | The E. COLI class-II cap-dependent transcription activation complex at the state 1 architecture | electron microscopy | E | — | — |
| 6PB6 | The E. COLI class-II cap-dependent transcription activation complex at the state 2 | electron microscopy | E | — | — |
| 6PMI | SIGM28-transcription initiation complex with specific promoter at the state 1 | electron microscopy | E | — | — |
| 6PMJ | Sigm28-transcription initiation complex with specific promoter at the state 2 | electron microscopy | E | — | 2 (best 0.80) |
| 6PMJ | SIGM28-transcription initiation complex with specific promoter at the state 2 | electron microscopy | E | — | — |
| 6XH7 | Cuer-tac without RNA | electron microscopy | E | — | — |
| 6XH8 | CueR-transcription activation complex with RNA transcript | electron microscopy | E | — | — |
| 6XH8 | Cuer-transcription activation complex with RNA transcript | electron microscopy | E | — | — |
| 6XL5 | Cryo-EM structure of ecmrr-rnap-promoter open complex (ecmrr-rpo) | electron microscopy | E | — | — |
| 6XLJ | Cryo-EM structure of ecmrr-rnap-promoter initial transcribing complex with 4-nt RNA transcript… | electron microscopy | E | — | — |
| 6XLL | Cryo-EM structure of E. COLI rnap-promoter initial transcribing complex with 5-nt RNA transcript… | electron microscopy | E | — | — |
| 6XLM | Cryo-EM structure of E.COLI rnap-DNA elongation complex 1 (RDE1) in ecmrr-dependent transcription | electron microscopy | E | — | — |
| 6XLN | Cryo-EM structure of E. COLI rnap-DNA elongation complex 2 (RDE2) in ecmrr-dependent transcription | electron microscopy | E | — | — |
| B7MFL0 | AlphaFold monomer V2.0 prediction for DNA-directed RNA polymerase subunit omega (B7MFL0) | predicted | A | — | — |
Experiment against prediction
- 6XLN chain E against the predicted model B7MFL0: TM-score 0.95, RMSD 0.95 Å
- 6XLL chain E against the predicted model B7MFL0: TM-score 0.95, RMSD 0.98 Å
- 6XL5 chain E against the predicted model B7MFL0: TM-score 0.95, RMSD 0.93 Å
- 6XLM chain E against the predicted model B7MFL0: TM-score 0.95, RMSD 0.96 Å
- 6XLJ chain E against the predicted model B7MFL0: TM-score 0.94, RMSD 1.04 Å
- 5UI8 chain K against the predicted model B7MFL0: TM-score 0.93, RMSD 1.10 Å
- 5UI8 chain K against the predicted model B7MFL0: TM-score 0.93, RMSD 1.10 Å
- 6B6H chain E against the predicted model B7MFL0: TM-score 0.91, RMSD 1.44 Å
- 6B6H chain E against the predicted model B7MFL0: TM-score 0.91, RMSD 1.44 Å
- 6PMJ chain E against the predicted model B7MFL0: TM-score 0.91, RMSD 1.42 Å
Elsewhere
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