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UniProt B7GZW7

Dihydroorotate dehydrogenase (quinone) (B7GZW7)

Dihydroorotate dehydrogenase (quinone) (UniProt B7GZW7), EC 1.3.5.2: 1 experimental structure and 1 predicted model on GenesisL1, 3 ligands bound, 9 pockets. Binding sites, druggability and experiment against prediction…

UniProt
B7GZW7
Protein
Dihydroorotate dehydrogenase (quinone)
EC
1.3.5.2
Experimental structures
1
Predicted models
1
Ligands
3
Pockets
9 · 2 records with a druggable one

Structures

2 records of B7GZW7 in the MolNFT archive: 1 experimental, 1 predicted.

EntryTitleMethodChainsLigandsPockets
7UT5Acinetobacter baumannii dihydroorotate dehydrogenase bound with inhibitor DSM186x-ray diffractionA, BOBR, FMN, ORO6 (best 0.82)
B7GZW7AlphaFold monomer V2.0 prediction for dihydroorotate dehydrogenase (quinone) (B7GZW7)predictedA—3 (best 0.79)

Ligands

  • FMN · Flavin mononucleotide · in 1 record
  • OBR · (4R)-7-methyl-N-[4-(pentafluoro-lambda~6~-sulfanyl)phenyl]imidazo[1,2-a]pyrimidin-5-amine · in 1 record
  • ORO · Orotic acid · in 1 record

Experiment against prediction

Elsewhere

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