UniProt B1MDI3
tRNA (guanine-N(1)-)-methyltransferase (B1MDI3)
tRNA (guanine-N(1)-)-methyltransferase (UniProt B1MDI3), EC 2.1.1.228: 94 experimental structures on GenesisL1, 56 ligands bound, 178 pockets. Binding sites, pockets, druggability and 3D structures in GL1X.
- UniProt
- B1MDI3
- Protein
- tRNA (guanine-N(1)-)-methyltransferase
- EC
- 2.1.1.228
- Experimental structures
- 94
- Predicted models
- 0
- Ligands
- 56
- Pockets
- 178 · 33 records with a druggable one
Structures
94 records of B1MDI3 in the MolNFT archive: 94 experimental, 0 predicted.
| Entry | Title | Method | Chains | Ligands | Pockets |
|---|---|---|---|---|---|
| 3QUV | Crystal structure of a tRNA-guanine-N1-methyltransferase from Mycobacterium abscessus | x-ray diffraction | A, B | — | — |
| 3QUV | Crystal structure of a tRNA-guanine-N1-methyltransferase from mycobacterium abscessus | x-ray diffraction | A, B | — | — |
| 6NW6 | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | SAM, SO4 | 5 (best 0.74) |
| 6NW6 | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | SO4 | — |
| 6NW7 | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | SO4 | — |
| 6QO2 | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | JAW | 5 (best 0.71) |
| 6QO2 | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JAW | — |
| 6QO3 | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | J9N | 4 (best 0.73) |
| 6QO3 | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | J9N | — |
| 6QO4 | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | 97T | 6 (best 0.73) |
| 6QO4 | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | 97T | — |
| 6QO6 | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | 5OB | 5 (best 0.72) |
| 6QO6 | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | 5OB | — |
| 6QOA | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | JBN | 6 (best 0.66) |
| 6QOA | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JBN | — |
| 6QOC | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | J9Q | — |
| 6QOD | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | FBB | — |
| 6QOE | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JBB | — |
| 6QOF | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | ADE | 6 (best 0.71) |
| 6QOF | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | ADE | — |
| 6QOG | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | JA8 | 5 (best 0.72) |
| 6QOG | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JA8 | — |
| 6QOH | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | 6GU, SO4 | 5 (best 0.70) |
| 6QOH | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | 6GU, SO4 | — |
| 6QOI | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | ABV | 5 (best 0.71) |
| 6QOI | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | ABV | — |
| 6QOJ | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JBH | — |
| 6QOK | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | J9T, SO4 | 4 (best 0.77) |
| 6QOK | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | J9T, SO4 | — |
| 6QOL | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JB5 | — |
| 6QOM | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JBE | — |
| 6QON | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | J9W, SO4 | — |
| 6QOO | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | JAB, SO4 | 7 (best 0.70) |
| 6QOO | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JAB, SO4 | — |
| 6QOP | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JBQ, SO4 | — |
| 6QOQ | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | JAE | 4 (best 0.71) |
| 6QOQ | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JAE | — |
| 6QOR | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | JBK, SO4 | 5 (best 0.71) |
| 6QOR | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JBK, SO4 | — |
| 6QOS | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | GOJ, SO4 | 6 (best 0.74) |
| 6QOS | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | GOJ, SO4 | — |
| 6QOT | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | 6SD | — |
| 6QOU | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JB8 | — |
| 6QOV | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | JAH | 8 (best 0.74) |
| 6QOV | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JAH | — |
| 6QOW | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | JBZ, SO4 | — |
| 6QOW | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JBZ, SO4 | — |
| 6QOX | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | JA5 | 4 (best 0.73) |
| 6QOX | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JA5 | — |
| 6QQQ | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | JDE, SO4 | — |
| 6QQQ | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JDE, SO4 | — |
| 6QQR | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | JDN | 5 (best 0.73) |
| 6QQR | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JDN | — |
| 6QQS | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JCZ | — |
| 6QQT | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JCH, SO4 | — |
| 6QQU | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | JF8 | 4 (best 0.74) |
| 6QQU | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JF8 | — |
| 6QQV | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | JEW, SO4 | 5 (best 0.73) |
| 6QQV | Crystal structure of trmd, a tRNA-(N1G37) methyltransferase, from mycobacterium abscessus in… | x-ray diffraction | A, B | JEW, SO4 | — |
| 6QQW | Crystal structure of TrmD, a tRNA-(N1G37) methyltransferase, from Mycobacterium abscessus in… | x-ray diffraction | A, B | JDQ, SO4 | 7 (best 0.72) |
34 records more on the page itself.
Ligands
- SO4 · Sulfate ion · in 42 records
- 5OB · 5-methoxybenzimidazole · in 2 records
- 6GU · 6-chloroguanine · in 2 records
- 97T · 2-(1,2-oxazol-5-yl)phenol · in 2 records
- ABV · 1,3-benzothiazol-2-amine · in 2 records
- ADE · Adenine · in 2 records
- GOJ · ethyl 1~{H}-pyrazole-4-carboxylate · in 2 records
- J9N · 5-thiophen-2-yl-4~{H}-pyrazol-3-amine · in 2 records
- J9T · methyl 2-azanylpyridine-4-carboxylate · in 2 records
- JA5 · methyl 2-(hydroxymethyl)-6~{H}-thieno[2,3-b]pyrrole-5-carboxylate · in 2 records
- JA8 · 5-bromanyl-1,3-benzothiazol-2-amine · in 2 records
- JAB · 1,2-oxazole-5-carbothioamide · in 2 records
- JAE · 1,3-benzothiazol-6-amine · in 2 records
- JAH · (6-phenylpyridin-3-yl)methanamine · in 2 records
- JAW · 1~{H}-indole-5-carboxamide · in 2 records
- JBK · 2-azanyl-3-nitro-phenol · in 2 records
- JBN · 1,2-oxazole-5-carboxamide · in 2 records
- JBZ · 6-methoxy-1,3-benzothiazole-2-carboxylic acid · in 2 records
- JCE · 5-[1-(pyridin-2-ylmethyl)indol-6-yl]-1~{H}-pyrazol-3-amine · in 2 records
- JD2 · 5-azanyl-3-[1-(pyridin-2-ylmethyl)indol-6-yl]-1~{H}-pyrazole-4-carbonitrile · in 2 records
- JDE · (3-methoxy-5-pyridin-3-yl-phenyl)methyl 1~{H}-pyrazole-4-carboxylate · in 2 records
- JDH · 5-azanyl-3-[1-[[4-[(4-methylpiperazin-1-yl) methyl]phenyl]methyl]indol-6-yl]-1~{H}-pyrazole-4-carbonitrile · in 2 records
- JDK · 3-[1-[[4-(piperidin-1-ylmethyl)phenyl]methyl]indol-6-yl]-1~{H}-pyrazol-5-amine · in 2 records
- JDN · 1~{H}-indol-5-ylboronic acid · in 2 records
- JDQ · 3-[1-(phenylmethyl)indol-6-yl]-1~{H}-pyrazol-5-amine · in 2 records
- JEE · 5-azanyl-3-[1-[[4-(morpholin-4-ylmethyl) phenyl]methyl]indol-6-yl]-1~{H}-pyrazole-4-carbonitrile · in 2 records
- JEH · 5-azanyl-3-[1-[[4-[(4-propan-2-ylpiperazin-1-yl) methyl]phenyl]methyl]indol-6-yl]-1~{H}-pyrazole-4-carbonitrile · in 2 records
- JEQ · 5-azanyl-3-[1-[[(3~{R})-1-(phenylmethyl)piperidin-3-yl]methyl]indol-6-yl]-1~{H}-pyrazole-4-carbonitrile · in 2 records
- JET · [3-(2-methoxy-2-oxidanylidene-ethoxy)phenyl]methyl 1~{H}-pyrazole-4-carboxylate · in 2 records
- JEW · 2-[[6-(5-azanyl-1~{H}-pyrazol-3-yl)indol-1-yl]methyl]benzenecarbonitrile · in 2 records
Elsewhere
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